Natural calcium phosphates from fish bones and their potential biomedical applications

Terzioğlu, Pınar; Öğüt, Hamdi; Kalemtaş, Ayşe

doi:10.1016/j.msec.2018.06.010

Cited by 101 publications

(64 citation statements)

References 105 publications

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“…By-products generated from fishing industry account for 40-50% of the total fish weight. Fishing industry by-products such as anchovy (Engraulis encrasicolus), carp (Cyprinus carpio), cuttlefish (Sepia officinalis), cod (Gadus morhua), tuna (Thunnus albacares), etc, can be used as animal feed or as a source of value-added minerals such as calcium phosphates [176]. Fish and shellfish by-products are also an important source of bioactive compounds imparting multiple health benefits.…”

Section: Fish and Shellfish Wastementioning

confidence: 99%

Bioactives from Agri-Food Wastes: Present Insights and Future Challenges

2020

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Sustainable utilization of agri-food wastes and by-products for producing value-added products (for cosmetic, pharmaceutical or food industrial applications) provides an opportunity for earning additional income for the dependent industrial sector. Besides, effective valorisation of wastes/by-products can efficiently help in reducing environmental stress by decreasing unwarranted pollution. The major focus of this review is to provide comprehensive information on valorisation of agri-food wastes and by-products with focus laid on bioactive compounds and bioactivity. The review covers the bioactives identified from wastes and by-products of plants (fruits, exotic fruits, vegetables and seeds), animals (dairy and meat) and marine (fish, shellfish seaweeds) resources. Further, insights on the present status and future challenges of sustainably utilizing agri-food wastes/by-products for value addition will be highlighted.

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Section: Fish and Shellfish Wastementioning

confidence: 99%

Bioactives from Agri-Food Wastes: Present Insights and Future Challenges

2020

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“…5,6 Different shapes of CPs such as powder, granule, block, and cement employ for hard tissues as a synthetic bone substitute. Fish bones can serve as a raw material for the production of high value-added compounds that can be used in various biomedical and pharmaceutical applications.…”

Section: Introductionmentioning

confidence: 99%

“…The recently published review summarizes the literature on the production of HA from fish bones and discusses their potential applications in biomedical field. 5,6 Different shapes of CPs such as powder, granule, block, and cement employ for hard tissues as a synthetic bone substitute. The block form of CPs is difficult fitting into the defects.…”

mentioning

confidence: 99%

In vitro apatite formation of calcium phosphate composite synthesized from fish bone

Asadollahzadeh

Rabiee

Salimi-Kenari

2019

Int J Applied Ceramic Tech

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Calcium phosphate‐based composite (CPC) is the main biomaterial substitute used for bone repair. Properties affecting bioactivity of this composite vary depending on the types of calcium phosphate crystalline phases. Hence, in this study, bioactivity behavior of novel CPC cement by the incorporation of calcium phosphate (CP), which was obtained from fish bones, dicalcium phosphate dehydrate, and chitosan solution, was monitored in simulated body fluid (SBF). In advance, the microstructure of CP produced by heat treatment (annealing) of fish bone was evaluated at two different temperatures 600 and 900°C. The X‐ray diffraction (XRD) results showed that there was no secondary phase formation aside from natural hydroxyapatite (HA) in bones annealed; and the annealing process enhanced the crystallinity of CP phase in the bone matrix particularly when annealed at 900°C. After incubation of CPC cement in SBF, bone bonding ability and producing of biomimetic HA coat on the CPC cement surface were confirmed using XRD, fourier‐transform infrared spectroscopy, and scanning electron microscopy. The analysis results show that needle‐like and cauliflower apatite layer with the crystallite size about 100 nm was grown on the surface of CPC cement after 28 days incubation in SBF. Regardless of above findings, we conclude that varying the annealing temperature has tremendous effect on the production of natural HA from fish bone with required properties and the ultimate morphology of obtained CPC cements after soaking is directly depended on the degree of crystallinity of the prepared natural HA.

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“…Alternatively, digestive enzymes from shrimp or fish viscera can be recovered and be successfully used as processing aids, that is, for the production of gelatin hydrolysate with antioxidant activities and/or angiotensin-I-converting enzyme (ACE) inhibitory activity [20,21] or the extraction of carotenoprotein from shrimp waste [22]. Fish bone is another by-product that can serve as a raw material for the production of high value-added compounds that can be used in various sectors including agrochemical, biomedical, food, and pharmaceutical industries [23]. Fish bone is considered as one of the potential biological sources to produce calcium phosphates [23,24].…”

Section: Fish-processing By-productsmentioning

confidence: 99%

“…Fish bone is another by-product that can serve as a raw material for the production of high value-added compounds that can be used in various sectors including agrochemical, biomedical, food, and pharmaceutical industries [23]. Fish bone is considered as one of the potential biological sources to produce calcium phosphates [23,24]. Fish bone can be applied to boost nutritional characteristics in seasoning powder [25].…”

Section: Fish-processing By-productsmentioning

confidence: 99%

Extraction, Characterization, and Application of Agricultural and Food Processing By-Products

Rawdkuen¹,

Ketnawa²

2020

Food Preservation and Waste Exploitation

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By-products originating from agricultural and food processing are considerable disposal problem for the industry because these waste streams emerge in huge quantities and often have direct impact on the economy and environmental pollution. However, at the same time, it constitute a rich but yet underutilized source of valuable components, which may find application as ingredients in the food and non-food industries. As a result, numerous projects are currently directed toward the utilization of agricultural and food processing by-products such as animal-based (skin, bone, flesh, and internal organs) and plant-based biomaterials (fruit peels and seeds, rice bran, and etc.). In the present work, we would like to focus on the potentialities and the current research of the compounds and extracts deriving from agro-industrial disposable wastes in the food-related utilization. The potential of selected by-products as a source of bioactive/functional compounds in terms of emerging and conventional techniques for extraction, characterization, biological activity monitoring and application of the extracts or isolated compounds as functional food ingredients or bio-based materials for food packaging are highlighted. Considering environmental effect and economic loss, agricultural and food processing by-products should be utilized in various innovative processes in the cause of beneficial product derivation.

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Natural calcium phosphates from fish bones and their potential biomedical applications

Cited by 101 publications

References 105 publications

Bioactives from Agri-Food Wastes: Present Insights and Future Challenges

Bioactives from Agri-Food Wastes: Present Insights and Future Challenges

In vitro apatite formation of calcium phosphate composite synthesized from fish bone

Extraction, Characterization, and Application of Agricultural and Food Processing By-Products

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