Natural Antioxidant and Antimicrobial Agents and Processing Technologies for the Design of Active Food Packaging Polymers

Chang, Boon Peng; Trinh, Binh M.; Tadele, Debela T.; Bandara, Nandika; Mekonnen, Tizazu H.

doi:10.1080/15583724.2023.2234464

Cited by 8 publications

(3 citation statements)

References 262 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2,3 Nutraceuticals and functional food ingredients are becoming increasingly popular because of their potential to support overall well-being and address specific health concerns. 2 The nutraceutical market is expected to experience significant growth, reaching an estimated value of $228.0 billion U.S. dollars (USD) by 2025, with a projected compound annual growth rate (CAGR) of 7% from 2019 to 2025. 2,3 This growth reflects an increasing consumer interest in natural health-promoting ingredients as part of a holistic approach to health and wellness.…”

Section: Introductionmentioning

confidence: 99%

“…2 The nutraceutical market is expected to experience significant growth, reaching an estimated value of $228.0 billion U.S. dollars (USD) by 2025, with a projected compound annual growth rate (CAGR) of 7% from 2019 to 2025. 2,3 This growth reflects an increasing consumer interest in natural health-promoting ingredients as part of a holistic approach to health and wellness. Quercetin and α-tocopherol are two bioactive nutraceuticals that have garnered attention, owing to their potential health benefits.…”

Section: Introductionmentioning

confidence: 99%

“…Chronic diseases, such as cancer, diabetes, and cardiovascular and respiratory conditions, currently account for approximately 71% of global death rates . The increasing prevalence of chronic diseases has generated heightened interest in nutraceuticals and functional food ingredients, which are believed to offer health benefits beyond basic nutrition and may aid in the prevention and management of various health conditions. , Nutraceuticals and functional food ingredients are becoming increasingly popular because of their potential to support overall well-being and address specific health concerns . The nutraceutical market is expected to experience significant growth, reaching an estimated value of $228.0 billion U.S. dollars (USD) by 2025, with a projected compound annual growth rate (CAGR) of 7% from 2019 to 2025. , This growth reflects an increasing consumer interest in natural health-promoting ingredients as part of a holistic approach to health and wellness.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Co-encapsulation of Quercetin and α-Tocopherol Bioactives in Zein Nanoparticles: Synergistic Interactions, Stability, and Controlled Release

Tadele,

Mekonnen

2024

ACS Appl. Polym. Mater.

Self Cite

View full text Add to dashboard Cite

This study examined the capabilities of zein-based nanoparticles for the co-delivery of quercetin and α-tocopherol. The results demonstrated an optimal encapsulation efficiency of 96% with an average particle size of 50−320 nm, highlighting the proficiency of the method. Over 60 days, the retention release profiles showed gradual reductions, with the Zein/Que/Toc (20:1:1) and Zein/Que/Toc (20:1:25) formulations exhibiting distinct dynamics. In vitro analyses revealed controlled release, with quercetin reaching 79.7% and α-tocopherol reaching 60.4% after 8 h. The Zein/Que/Toc (20:1:5) combination exhibited a notable release of 73.1% over the same span, indicating a synergistic or stabilizing interplay between the co-encapsulated agents, which is beneficial for digestion. ATR-FTIR, rheology, and fluorescence spectroscopy investigations demonstrated key molecular interactions, including hydrogen bonding and hydrophobic forces. The integration of surfactants enhanced the photostability and retention of both bioactive compounds. This study emphasizes the vast potential of zein-based nanoparticles for bioactive co-delivery, with the Zein/ Que/Toc (20:1:5) formulation emerging as a viable candidate. These findings have implications for the pharmaceutical, nutraceutical supplement, drug, and functional food domains.

show abstract