Natural alkaloids: basic aspects, biological roles, and future perspectives

Qiu, Shi; Sun, Hui; Zhang, Aihua; Xu, Huibin; Ge, Yan; Han, Ying; Wang, Xijun

doi:10.1016/s1875-5364(14)60063-7

Cited by 150 publications

(114 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…T hey aff ect the microorganisms c ausi ng leakag e of proteins and c ertai n enz ymes from t heir c ells (Zablotowicz et al , 1996). Alk aloids ar e commonl y found to hav e antimicrobial properties ag ainst b ot h Gram -positiv e and Gram-negativ e bacteri a (G uv en et al, 2010 (Qiu et al, 2014 The GC-MS anal ysis of the antimicrobial et hanolic extrac t of U. l act uc a indicat ed the presenc e of maj or components whic h confirmed that found by t he phyt oc hemic al anal ysis.…”

Section: Discussionmentioning

confidence: 99%

Seasonal Variation of the Antibacterial Activity of some Seaweeds against Multi Drug Resistant Pathogenic bacterial Strains

El-Shouny¹,

Gaafar²,

Ismail³

et al. 2017

Egypt. J. Exp. Biol. (Bot.)

View full text Add to dashboard Cite

Season al v ariation of the a ntibacteri al a ctiv ity of some sea wee ds against multi drug resi stant patho genic bacterial strai ns ABSTRACT:The present s tud y aimed t o eval uat e the eff ect of seas onal v ariation of the antibact erial ac tivit y of s ome s eaw eed s. Pat hogenic bact erial is olates wer e c ollec ted from adult p atients of T ant a Educ ati onal Hospitals, Microbiolog y Labs, i ncluding Escherichi a c oli , Kl ebsi ella pneumoniae and Prot eus mirabilis ( Gram-negativ e bact eria) which w ere t he mai n caus e of urinar y trac t infec tion (UT I). Three s eaw eeds (macr oalgae) belonging to differ ent divisions viz . Ulva lactuca (C hlorop hyt a), S argass um vul gar e (Phaeophyt a) and Jania rubens (Rhodophyt a) were coll ect ed s eas onall y d uring 2015 -2016 from Abu-Qir B ay, Al exandria, Eg ypt. Diff erent solvents (85% each of ethanol, met hanol and acetone) were us ed to extr act the antimicrobial m ateri al. T he antibact erial activit y w as mor e obs erved during winter and spring seas ons f or green algae while it w as higher i n s ummer and autum n s eas ons f or red algae. T he mos t eff ectiv e s eaweeds extrac t agains t the tes ted UT I bact erial is olate s w as the et hanol extrac t of U. l act uc a c ollec ted i n the spring season. T he g as c hrom atograp hy mass spec trometr y (GC -MS) was d etermi ned to U. lact uc a antibact erial extrac t and revealed it s high cont ent of phenolic compounds. T he t oxicit y t est rev eal ed t hat U . lactuca antibac teri al extrac t c aused no haemol ysis to the red blood cells implyi ng its saf et y as a propos ed drug for UT I bact erial diseas e.

show abstract

Section: Discussionmentioning

confidence: 99%

Seasonal Variation of the Antibacterial Activity of some Seaweeds against Multi Drug Resistant Pathogenic bacterial Strains

El-Shouny¹,

Gaafar²,

Ismail³

et al. 2017

Egypt. J. Exp. Biol. (Bot.)

View full text Add to dashboard Cite

show abstract

“…chelerythrine) [22], and antihyperglycemic activities (e.g. piperine) [23]. These phytochemicals may contribute analgesic, anti-pyretic, protective, antibacterial, anti-ulceration and ameliorating properties of ocimum gratissimum leaves.…”

Section: Resultsmentioning

confidence: 99%

In vitro Medicinal Studies on Ocimum gratissimum Leaves

2016

ARC Journal of Pharmaceutical Sciences

View full text Add to dashboard Cite

“…It was also reported to have cholinomimetic, vasodilatory, antiarrhythmic, antihyperglycemic activities [51], analgesic and antibacterial properties [52][53][54], though they can be toxic too [55]. Studies have shown that all the plants studied have the tendency to treat these ailments and they all contain alkaloids.…”

Section: Phytochemical Screening Of Plants Extractsmentioning

confidence: 99%

Qualitative and Quantitative Phytochemical Screening of Some Plants Used in Ethnomedicine in the Niger Delta Region of Nigeria

Ajuru¹,

Williams²,

Ajuru³

2017

JFNS

View full text Add to dashboard Cite

Qualitative and quantitative phytochemical screening of six plants used in ethnomedicine in the Niger Delta region of Nigeria was carried out to identify and quantify the bioactive compounds present in these highly medicinal plants. The plants studied were Phyllanthus amarus Schum and Thonn, Euphorbia heterophylla Linn., Senna occidentalis L., Piper nigrum L., Ageratum conyzoides L. and Gongronema latifolium Benth. Ethanolic and aqueous extracts of leaves of the plant species were screened for the presence of alkaloid, anthraquinone, coumarin, flavonoid, phenol, quinone, saponin, tannin, sugar and glycoside and quantitative study was also carried out using Standard method. Qualitative study indicated the presence of all the phytochemicals in the ethanolic extracts of P. amarus and E. heterophylla, and absence of anthraquinone in S. occidentalis, P. nigrum, A. conyzoides and G. latifolium. Also, absence of coumarin in S. occidentalis, and phenol in G. latifolium. The aqueous extract indicated the presence of all the phytochemicals in A. conyzoides and presence of alkaloid, tannin, sugar and glycoside in other plant species studied. Quantitative analysis showed variable amounts of pharmacologically important secondary metabolites such as alkaloids, tannins, flavonoid, saponins and phenol in all the plants investigated. The different phytochemicals are shown to perform different biological activities in humans and animals. These compounds can be harnessed for industrial and pharmaceutical utilization.

show abstract

Natural alkaloids: basic aspects, biological roles, and future perspectives

Cited by 150 publications

References 47 publications

Seasonal Variation of the Antibacterial Activity of some Seaweeds against Multi Drug Resistant Pathogenic bacterial Strains

Seasonal Variation of the Antibacterial Activity of some Seaweeds against Multi Drug Resistant Pathogenic bacterial Strains

In vitro Medicinal Studies on Ocimum gratissimum Leaves

Qualitative and Quantitative Phytochemical Screening of Some Plants Used in Ethnomedicine in the Niger Delta Region of Nigeria

Contact Info

Product

Resources

About