“…The incidence and mortality of malignant melanoma is steadily increasing among Caucasians (Chamberlain and Ng, 2009; Linos et al., 2009; Mills and Messina, 2009) and in other populations, including Asians (Ishihara et al., 2004). Surgical treatment is effective for early stage melanoma, but new strategies are required for patients with advanced melanoma, which is highly resistant to conventional chemo‐ and radiation therapy.…”