Nationwide incidence and treatment pattern of benign prostatic hyperplasia in Korea

Abstract

PurposeTo investigate the incidence of benign prostatic hyperplasia (BPH) in Korea and treatment patterns for 3 years after the diagnosis in a nationwide database.Materials and MethodsWe created a cohort of patients diagnosed of BPH between 2007 and 2011 from the Health Insurance Review & Assessment database, a nationwide database of reimbursement. The diagnosis of BPH was defined as having the diagnosis of BPH (N40.0 in International Classification of Diseases, 10th revision) as a primary or secondary diagnosis ≥2 times in 2008. The incidence of BPH in 2008 was calculated. Treatment patterns were determined in 3 months interval and traced for 3 years. The incidence and timing of surgery were also determined. For patients taking medications preoperatively, medication-free rate was calculated.ResultsThe incidence of BPH was 2,105 per 100,000 men (mean age, 59.7±11.4 years), and increased with age. Surgery was performed for 7,955 patients (2.1%), half of the surgery being performed within the first 6 months. Transurethral resection of the prostate was the most commonly performed surgery. The proportion of treatment increased with age until the 7th decade of life. The patients taking medication for >1 year after the initial diagnosis was 21.4%. On average, 82% of patients became medication-free at postoperative 1 year. For patients taking preoperative anticholinergics, 1 year medication-free rate was 73.3%.ConclusionsThe incidence of BPH increased with age. Surgery was performed in 2.1% of patients. More than 4/5 patients discontinued medication after surgery, while patients taking preoperative anticholinergics were less likely to.

Corn silk extract improves benign prostatic hyperplasia in experimental rat model

“…The incidence rate of urological diseases is increasing, especially in middle-aged men, and the prevalence of such diseases increases with age; an estimated 50% of men exhibit histologic evidence of benign prostatic hyperplasia (BPH) by age 50, increasing to 80% at age 80 [ 6 7 ]. BPH is a complex urinary disease that results in abnormalities due to prostate enlargement, which causes obstruction of the bladder and lower urinary tract [ 8 ].…”

“…BPH is a complex urinary disease that results in abnormalities due to prostate enlargement, which causes obstruction of the bladder and lower urinary tract [ 8 ]. Obstruction of urination normally leads to symptoms such as urinary frequency, urination disorder, and bladder occlusion, which may be symptomatic or asymptomatic depending on the patient [ 6 7 8 ]. Although the mechanism underlying BPH pathogenesis has not been fully elucidated, the most prevalent theory is that testosterone and dihydrotestosterone (DHT) are involved in the proliferation of prostate cells.…”

Diagnostic Utility of Amacr Expression to Differentiate Prostate Carcinoma From Benign Hyperplasia of Prostate- A Hospital Based Cross-Sectional Study

“…[23] Regarding BHP, it is also a disease of men of older age group with mean age group above 50 years as revealed by previous studies. [24,25] In present study, the mean age for BHP is 62.79 (±8.67) and statistically it is not helpful to differentiate with prostate cancer (Table-1).…”

Health‐related quality of life in patients undergoing TURP: Translating evidence into urological nursing practice

“…1 This condition triggers pressure on the urethra causing bladder outflow obstruction, and hence a variability of lower urinary tract symptoms (LUTS). 5,6 In order to reduce the complexities of BPH, innovative treatments developed in clinical practice have been widely employed with various efficacy and safety profiles. 4 It is also reported that BPH increases with age and affect more than 70% of elderly males.…”

“…4 It is also reported that BPH increases with age and affect more than 70% of elderly males. 5,6 In order to reduce the complexities of BPH, innovative treatments developed in clinical practice have been widely employed with various efficacy and safety profiles.…”