National Trends in Parathyroid Surgery from 1998 to 2008: A Decade of Change

Greene, Andrew B.; Butler, Robert S.; McIntyre, Shannon; Barbosa, Germán; Mitchell, Jamie; Berber, Eren; Siperstein, Allan; Milas, Mira

doi:10.1016/j.jamcollsurg.2009.05.029

Cited by 144 publications

(83 citation statements)

References 36 publications

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“…27 This evolution was made possible by the development of highresolution radiological techniques and the development of the rapid IOPTH assay. Sonography and technetium-99m-sestamibi ( 99m Tc-sestamibi) scintigraphy are the most commonly used imaging techniques for the demonstration of parathyroid lesions.…”

Section: Preoperative Localization and Surgical Treatmentmentioning

confidence: 99%

Parathyroid tumors and related disorders

2011

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Primary hyperparathyroidism (P-HPT) is a common endocrine disorder that occurs as a result of adenomas (80-85%), hyperplasias (10-15%) or carcinomas (o1%) of the parathyroid glands. Molecular genetic analyses of heritable P-HPT syndromes have provided considerable insight into the understanding of sporadic parathyroid tumors and hyperplasias. This review will focus on the criteria for classification of parathyroid proliferative disorders and will highlight our understanding of these lesions at the molecular level. Advances in radiological imaging techniques together with the rapid intraoperative parathyroid hormone assay will be reviewed with respect to current treatment approaches for P-HPT.

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Section: Preoperative Localization and Surgical Treatmentmentioning

confidence: 99%

Parathyroid tumors and related disorders

2011

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“…3 The only therapeutic option for complete cure of primary hyperparathyroidism is surgery, with reported success rates of greater than 95% for the reference standard of bilateral neck exploration performed by an experienced surgeon. 4 Minimally invasive parathyroidectomy with a unilateral surgical approach is rapidly becoming the standard of care in an effort to lower complication rates, reduce costs, shorten hospital stays, and improve cosmetic results. [4][5][6] Preoperative localization and lateralization of abnormal parathyroid glands are integral to the performance of unilateral minimally invasive parathyroidectomy.…”

mentioning

confidence: 99%

4D-CT for Preoperative Localization of Abnormal Parathyroid Glands in Patients with Hyperparathyroidism: Accuracy and Ability to Stratify Patients by Unilateral versus Bilateral Disease in Surgery-Naïve and Re-Exploration Patients

Kelly

Hamberg

Hunter

2013

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE: 4D-CT is an emerging technique that uses high-resolution images, multiplanar reformats, and perfusion characteristics to identify abnormal parathyroid glands in patients with hyperparathyroidism. This study evaluates the accuracy of 4D-CT for localization and lateralization of abnormal parathyroid glands in preoperative planning for minimally invasive parathyroidectomy vs bilateral neck exploration at a tertiary referral center.

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“…10 The same has been made possible because of development of preoperative localization techniques which includes high resolution radiographic techniques and rapid intraoperative parathormone assay. However, USG and the Tc99m sestamibi scan are the most commonly employed methods for demonstrating parathyroid lesions.…”

Section: Discussionmentioning

confidence: 99%

A large parathyroid adenoma presenting with pathological fractures in a young male

Sahu

Galagali

Singh

et al. 2015

Int J Otorhinolaryngol Head Neck Surg

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Parathyroid adenoma is the common cause of primary hyperparathyroidism and usually presents with features of hypercalcaemia. In the present case report, we describe a case of a large adenoma of the parathyroid gland presenting with pathological fractures. A 42 year old Male presented with bony pains and fracture of the left humerus after a trivial trauma. A detailed clinical examination and laboratory studies revealed hypercalcaemia secondary to hyperparathyroidism. The patient underwent targeted parathyroidectomy of the involved gland after appropriate preoperative localization. Histopathology of the resected specimen was consistent with parathyroid adenoma. Conclusion is a common cause of primary hyperparathyroidism is a common endocrine disorder occurring as a result of Parathyroid adenoma in 80-85% cases. Patients usually present with symptoms related to hypercalcaemia. A high index of suspicion, careful preoperative workup, localization of the affected gland(s) and surgical excision ensures a successful cure.

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National Trends in Parathyroid Surgery from 1998 to 2008: A Decade of Change

Cited by 144 publications

References 36 publications

Parathyroid tumors and related disorders

Parathyroid tumors and related disorders

4D-CT for Preoperative Localization of Abnormal Parathyroid Glands in Patients with Hyperparathyroidism: Accuracy and Ability to Stratify Patients by Unilateral versus Bilateral Disease in Surgery-Naïve and Re-Exploration Patients

A large parathyroid adenoma presenting with pathological fractures in a young male

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