National Experience with Extracorporeal Membrane Oxygenation for Newborn Respiratory Failure

Toomasian, John M; Snedecor, Sandy M.; Cornell, Richard G.; Cilley, Robert E.; Bartlett, Robert H.

doi:10.1097/00002480-198804000-00011

Cited by 173 publications

(46 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ECMO has been employed to support thousands of infants with PPHN from virtually any cause (315). There is retrospective evidence that it is more effective than conventional medical therapy in treating persistent pulmonary hypertension in general (315) and from specific causes such as diaphragmatic hernia (316) and Group B streptococcal sepsis (314).…”

Section: Extracorporeal Membrane Oxygenationmentioning

confidence: 99%

“…There is retrospective evidence that it is more effective than conventional medical therapy in treating persistent pulmonary hypertension in general (315) and from specific causes such as diaphragmatic hernia (316) and Group B streptococcal sepsis (314). However, the historical controls used for these retrospective studies are probably inappropriate (317,318).…”

Section: Extracorporeal Membrane Oxygenationmentioning

confidence: 99%

See 1 more Smart Citation

Persistent pulmonary hypertension of the newborn.

Morin¹,

Stenmark²

1995

Am J Respir Crit Care Med

131

View full text Add to dashboard Cite

Section: Extracorporeal Membrane Oxygenationmentioning

confidence: 99%

Section: Extracorporeal Membrane Oxygenationmentioning

confidence: 99%

Persistent pulmonary hypertension of the newborn.

Morin¹,

Stenmark²

1995

Am J Respir Crit Care Med

131

View full text Add to dashboard Cite

“…Since then, many doctors in the United States (3,(8)(9)(10)(14)(15)(16) have employed ECMO to manage the neonates with not only CDH but other respiratory failures such as meconium aspiration. Bartlett and coworkers (13) have also proposed the neonatal ECMO registry 10 collect data and to evaluate the efficacy of ECMO. We have participated in this ECMO registry since 1986.…”

Section: Discussionmentioning

confidence: 99%

Management of Congenital Diaphragmatic Hernia by Extracorporeal Membrane Oxygenation (ECMO)

Nagaya

Tsuda²,

Murahashi³

et al. 1991

Eur J Pediatr Surg

View full text Add to dashboard Cite

The purpose of this study was to evaluate the efficacy of extracorporeal membrane oxygenation (ECMO) for patients with congenital diaphragmatic hernia (CDH). Ten patients whose mortality was predicted to be more than 80% with previous therapeutics, were selected to use ECMO over the past five years. Patients were placed on ECMO by cannulating the right jugular vein and the right carotid artery. ECMO was started at 34.3 hours after birth on an average, and the average time on ECMO was 96.3 hours. Seven patients (70%) survived, and six out of them are in good health without any sequelae. In particular, all five patients whose pathological condition needing ECMO was persistent fetal circulation (PFC), survived. Therefore we believe ECMO is highly beneficial to overcome the condition of PFC. The survival rate of CDH patients under 24 hours of age in our hospital is 76.2% (16/21 cases) over the last 5 years, and it has improved compared with 57.1% (12/21 cases) before then. The fact that some of the critical patients who were lethal with conventional management, have been successfully treated by ECMO, played a great role in this improvement.

show abstract

“…These data records are currently considered to be an accurate representation of the bypass period; however, upon investigation, they appear to represent a blending of data points towards accepted norms and a minimization of outlier data points (54,55). Once these patient specific and frequent data points are available, they can to be used in conjunction with other clinical databases such as the Society of Thoracic Surgeons Congenital Heart Surgery (STS) (56), Pediatric Cardiac Critical Care Consortium (PC4) (57,58), and Pediatric Acute Care Cardiology Collaborative (PAC3) (59-61), and Extracorporeal Life Support Organization Registry (ELSO) (62,63) to examine the relationships between patient parameters and practices utilized during CPB with short and long term patient outcomes (64). With the development of these analytic tools, the impact on circuit construction and patient monitoring will enable the better targeting of RBC transfusion to individual patients or patient populations.…”

Section: Physical Parameter Measurements and Data Capturementioning

confidence: 99%

Recent innovations in perfusion and cardiopulmonary bypass for neonatal and infant cardiac surgery

Sturmer¹,

Beaty²,

Clingan³

et al. 2018

Transl Pediatr

View full text Add to dashboard Cite

Abstract:The development and refinement of cardiopulmonary bypass (CPB) has made the repair of complex congenital heart defects possible in neonates and infants. In the past, the primary goal for these procedures was patient survival. Now that substantial survival rates have been achieved for even the most complex of repairs in these patients, focus has been given to the reduction of morbidity. Although a necessity for these complex neonatal and infant heart defect repairs, CPB can also be an important source of perioperative complications. Recent innovations have been developed to mitigate these risks and is the topic of this review. Specifically, we will discuss improvements in minimizing blood transfusions, CPB circuit design, monitoring, perfusion techniques, temperature management, and myocardial protection, and then conclude with a brief discussion of how further systematic improvements can be made in these areas.

show abstract

National Experience with Extracorporeal Membrane Oxygenation for Newborn Respiratory Failure

Cited by 173 publications

References 0 publications

Persistent pulmonary hypertension of the newborn.

Persistent pulmonary hypertension of the newborn.

Management of Congenital Diaphragmatic Hernia by Extracorporeal Membrane Oxygenation (ECMO)

Recent innovations in perfusion and cardiopulmonary bypass for neonatal and infant cardiac surgery

Contact Info

Product

Resources

About