Nation-wide vector surveillance on Zika and Dengue did not indicate transmission of the American lineage-pandemic Zika virus in India

Kumar, N. Pradeep; Kumar, Anil; Panneer, D.; Abidha, S.; Muthukumaravel, S.; Sankari, T.; Ajithlal, P.M.; Mathew, Jessu; Koothradan, Suhana; Paramasivan, R; Muniyaraj, M.; Singh, Himmat; Saxena, Rekha; Vijayachari, P.; Sunish, I. P.; Shriram, A N; Dutta, Prafulla; Patgiri, Saurav Jyoti; Bhattacharyya, D. R.; Hoti, S.L.; Chattopadhyay, Dr.Saswati; Roy, Subarna; Mahapatra, Namita; Chand, Gyan; Mishra, Amit; Barde, Pradip V; Jambulingam, P.

doi:10.1016/j.ijid.2021.09.074

Cited by 5 publications

(2 citation statements)

References 35 publications

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“…We used archived mosquito samples collected as part of the previously conducted project “Vector Surveillance for ZIKV in Selected High-Risk Areas” [ 16 , 17 ]. Ae.…”

Section: Methodsmentioning

confidence: 99%

Molecular Evidence of Wolbachia Species in Wild-Caught Aedes albopictus and Aedes aegypti Mosquitoes in Four States of Northeast India

Vinayagam,

Nirmolia,

Chetry

et al. 2023

Journal of Tropical Medicine

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Wolbachia, a Gram-negative intracellular bacterium, naturally infects many arthropods, including mosquito vectors responsible for the spread of arboviral diseases such as Zika, chikungunya, and dengue fever. Certain Wolbachia strains are involved in inhibiting arbovirus replication in mosquitoes, and this phenomenon is currently being studied to combat disease vectors. A study was conducted in four states in north-eastern India to investigate the presence of natural Wolbachia infection in wild-caught Aedes albopictus and Aedes aegypti mosquitoes, the established vectors of dengue. The detection of a Wolbachia infection was confirmed by nested PCR and sequencing in the two mosquito species Ae. aegypti and Ae. albopictus. Positivity rates observed in Ae. aegypti and Ae. albopictus pools were 38% (44 of 115) and 85% (41 of 48), respectively, and the difference was significant (chi-square = 28.3174, p = 0.00000010). Sequencing revealed that all detected Wolbachia strains belonged to supergroup B. Although Wolbachia infection in Ae. aegypti has been previously reported from India, no such reports are available from north-eastern India. Data on naturally occurring Wolbachia strains are essential for selecting the optimal strain for the development of Wolbachia-based control measures. This information will be helpful for the future application of Wolbachia-based vector control measures in this part of the country.

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“…We used archived mosquito samples collected as part of the previously conducted project “Vector Surveillance for ZIKV in Selected High-Risk Areas” [ 16 , 17 ]. Ae.…”

Section: Methodsmentioning

confidence: 99%

Molecular Evidence of Wolbachia Species in Wild-Caught Aedes albopictus and Aedes aegypti Mosquitoes in Four States of Northeast India

Vinayagam,

Nirmolia,

Chetry

et al. 2023

Journal of Tropical Medicine

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“…An estimated 700,000 individuals in the Americas were infected with ZIKV by 2016. Although the ZIKV epidemic has since subsided, the virus continues to circulate in the Americas and other regions of the world (10,11). As of 2019, active transmission has been reported globally in 87 countries and territories (12).…”

Section: Introductionmentioning

confidence: 99%

Drugs to limit Zika virus infection and implication for maternal-fetal health

Kumar¹,

Kumar²,

Jose³

et al. 2022

Front. Virol.

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Although the placenta has robust defense mechanisms that protect the fetus from a viral infection, some viruses can manipulate or evade these mechanisms and disrupt physiology or cross the placental barrier. It is well established that the Zika virus is capable of vertical transmission from mother to fetus and can cause malformation of the fetal central nervous system (i.e., microcephaly), as well as Guillain-Barre syndrome in adults. This review seeks to gather and assess the contributions of translational research associated with Zika virus infection, including maternal-fetal vertical transmission of the virus. Nearly 200 inhibitors that have been evaluated in vivo and/or in vitro for their therapeutic properties against the Zika virus are summarized in this review. We also review the status of current vaccine candidates. Our main objective is to provide clinically relevant information that can guide future research directions and strategies for optimized treatment and preventive care of infections caused by Zika virus or similar pathogens.

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Diversity analysis, distribution and abundance of mosquito assemblages Diptera: Culicidae at urban sector from southwestern Colombia.

Bedoya-Rodríguez

Fletcher²,

Pelegrín-Ramírez

2023

Preprint

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The Culicidae family (mosquitoes) has great relevance worldwide, due to its involvement in the generation of several diseases. The department of Cauca in Colombia characterize as a region with influence of several vector-borne diseases. The purpose of this study is to analyze the ecological diversity and distribution of mosquitoes with potential transmitters of diseases in a particular urban area of the municipality of Santander de Quilichao. This is one of the first studies of its kind in this municipally. Mosquito collections were carried out during the rainy and dry seasons of 2022, between 17:00 to 19:00. Morphological keys were used for species identification. For the analysis of diversity comparison vs. sampling points, Simpson's index was used, dendrogram, rarefaction curve and non-metric multidimensional scaling (nMDS). In the statistical analysis of species-abundances, ANOVA were applied to determine if there were significant differences regarding abundance. A total of 1116 culicid specimens were collected. The 59.4% were mosquitoes of the species Aedes aegypti, 18.5% Culex quinquefasciatus, 18.2% Aedes albopictus and 3.9% Psorophora ferox, being the rainy season important for their survival. ANOVA analysis showed that the mean abundance of Aedes aegypti was significantly different from the other species. This study is broadly consistent with other studies in the tropical American context where the abundance of Culicidae is more representative in the rainy season. The results suggest a wide presence of Aedes mosquitoes in natural and artificial habitats, showing the importance of establishing controls and permanent epidemiological surveillance in this region.

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Nation-wide vector surveillance on Zika and Dengue did not indicate transmission of the American lineage-pandemic Zika virus in India

Cited by 5 publications

References 35 publications

Molecular Evidence of Wolbachia Species in Wild-Caught Aedes albopictus and Aedes aegypti Mosquitoes in Four States of Northeast India

Molecular Evidence of Wolbachia Species in Wild-Caught Aedes albopictus and Aedes aegypti Mosquitoes in Four States of Northeast India

Drugs to limit Zika virus infection and implication for maternal-fetal health

Diversity analysis, distribution and abundance of mosquito assemblages Diptera: Culicidae at urban sector from southwestern Colombia.

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