Abstract:Nasal pathogen detection sensitivities can be as low as 70% despite advances in molecular diagnostics. This may be linked to the choice of sampling method. A diagnostic test accuracy review for sensitivity was undertaken to compare sensitivity of swabbing to the nasopharynx and extracting nasal aspirates, using the PRISMA protocol, Cochrane rapid review methodology, and QUADAS-2 risk of bias tools, with meta-analysis of included studies. Sensitivities were calculated by a consensus standard of positivity by ei… Show more
“…We agree that nasal wash or nasopharyngeal aspirate, which has previously been demonstrated to be useful when testing for different viruses, Ref. [ 3 ] may also be an interesting candidate to test for SARS-CoV-2 in a self-collected environment.…”
“…We agree that nasal wash or nasopharyngeal aspirate, which has previously been demonstrated to be useful when testing for different viruses, Ref. [ 3 ] may also be an interesting candidate to test for SARS-CoV-2 in a self-collected environment.…”
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