Nasopharyngeal chordoma presenting with metastases

Singh, Waryam; Kaur, Amar

doi:10.1017/s0022215100103494

Cited by 16 publications

(2 citation statements)

References 7 publications

(5 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In descending order of occurrence, the organs and tissues involved by metastasis include the lungs, lymph nodes, liver, bone, skin, muscle, peritoneum, heart, pleura, retroperitoneum, spleen, dura mater, kidney, and the adrenal glands. 1,[3][4][5][6][7][8][9][10][11]13,18,[22][23][24][25]27,29,30,32,33,35,36,38,39,[41][42][43][44][45][46][47][48][49][50] Markwalder, et al, 29 have suggested that metastasis is more common with spinal rather than clival chordomas because most tumor cells reach the circulation by invading large veins. Chambers and Schwinn 10 have suggested that irradiation may play some role in the genesis of metastasis, whereas surgery, length of survival, age, and sex do not.…”

Section: Metastasis Of Chordomasmentioning

confidence: 99%

Surgical seeding of chordomas

Arnautović¹,

Al‐Mefty²

2001

Journal of Neurosurgery

View full text Add to dashboard Cite

show abstract

Section: Metastasis Of Chordomasmentioning

confidence: 99%

Surgical seeding of chordomas

Arnautović¹,

Al‐Mefty²

2001

Journal of Neurosurgery

View full text Add to dashboard Cite

show abstract

“…The most common sites of tumor extension in the skull base are the nasopharynx, maxilla, and the frontal sinus. 5,21,31,35,39,48 …”

Section: Local Tumor Recurrence and Progressionmentioning

confidence: 99%

Surgical seeding of chordomas

Ki¹,

Al‐Mefty²

2001

FOC

View full text Add to dashboard Cite

Object Chordomas have a high propensity for local recurrence and progression, as well as for systemic and cerebrospinal fluid metastasis. The authors identified and analyzed a series of patients with chordomas, focusing on an underrecognized entity—surgical seeding. Methods In a retrospective analysis of 82 patients with chordomas treated over a 10-year period (1990–2000) the authors found six patients (7.3%) in whom surgical seeding had occurred. In five (83%) of these patients the primary tumor was located at the clivus. In one (17%) the tumor was present in the cervical region. There were two male (33%) and four female patients (67%) with a mean age of 34 years. The seeding sites, which were separate from the primary tumor, were located along the operative route or in the abdomen where fat was removed. The seeding was diagnosed 5 to 15 months after surgery (mean 12 months). One seeding site was present in five patients and 17 seeding sites were present in one patient. The involved tissues included mucosa, bone, dura, muscle, and fat. After resection, all seedings were documented histologically. Conclusions Seeding of chordomas occurs along the operative route and at distant locations where fat is harvested. Early diagnosis and aggressive surgical treatment are recommended. Based on the results of this study, it is suggested that surgical techniques, postoperative irradiation, the neuroradiological follow-up protocol, and even research on chordomas should be reevaluated.

show abstract

Rachen und Tonsillen

Otto¹

1999

Spezielle Pathologische Anatomie

View full text Add to dashboard Cite

Nasopharyngeal chordoma presenting with metastases

Cited by 16 publications

References 7 publications

Surgical seeding of chordomas

Surgical seeding of chordomas

Surgical seeding of chordomas

Rachen und Tonsillen

Contact Info

Product

Resources

About