Nasopharyngeal angiofibroma in a patient with haemophilia A: a bleeding tumour in a bleeding‐prone patient

Abstract

Nasopharyngeal angiofibroma is a highly vascular tumour which occurs almost exclusively in adolescent males. Although it is histologically benign, it may cause serious clinical problems because of its tendency to bleed profusely during surgery. This paper presents the first case of nasopharyngeal angiofibroma in a patient with haemophilia A, another well-known disease of bleeding tendency. In this case the tumoural mass was surgically removed with effective factor VIII replacement without any bleeding complication.

Antimicrobial activity of Ankaferd Blood Stopper® against nosocomial bacterial pathogens

“…Hospitalized patients may experience various life-threatening infection-induced hemorrhages, most frequently due to coagulation defects such as thrombocytopenia and disseminated intravascular coagulation [3,[29][30][31]. Ankaferd-induced formation of the protein network with vital erythroid aggregation includes the entire physiologic hemostatic process [1,8].…”

Consumptive coagulopathy complicating juvenile angiofibroma

“…6 Difficulties with haemostasis have been encountered in cases of juvenile angiofibroma and attributed to underlying clotting derangement. 11,12 However, it is important to emphasize that we found no association between laboratory-confirmed coagulopathy and any perioperative haemorrhagic or thrombotic complications. One of the patients studied demonstrated a marked coagulopathy which resolved rapidly following surgery.…”

Case Report: Massive epistaxis from juvenile angiofibroma in an adolescent with severe haemophilia A

“…To our knowledge, there is only one previous case of JA and concomitant haemophilia in the English literature, twice reported by Ozturk et al in 1999 3 and by Celiker et al in 4 . In their case, the preliminary diagnosis of JA was confirmed by biopsy at a different medical centre, where massive haemorrhage jeopardized the patient's life.…”