Nasopalatine duct cyst, called the incisive canal cyst, described in literature as a cystis canalis nasopalatine or cystis canalis incisive, is the most common non-odontogenic cyst occurring in the oral cavity. It develops in the midline palate around the incisive foramen from debris of nasopalatine duct's epithelium. The etiology is unknown, although it is believed that some of the irritants may have an impact on its development. Cyst develops slowly destroying the alveolar bone of the maxilla. Typically, the process is asymptomatic and is detected accidentally on radiograph. Clinical diagnosis is made due to X-rays, but only histopathology can confirm the results. The treatment of choice is total enucleation of pathological changes. The following article presents a case of nasopalatine duct cysts, which is diagnosed and treated at the Faculty of Dentistry in Skopje. The case is characteristic regarding the symptomatology, as well as the need of differentiation from other pathological changes within the region, as well as the need for proper treatment.