Nasolabial Flaps in the Treatment of MRONJ

Abstract

Medication-related osteonecrosis of the jaw (MRONJ) occurs as a side effect of several drug classes, including antiresorptives and antiangiogenics. Its treatment may be approached in a number of different ways. The report below outlines a notable surgical case wherein sequestrectomy (with the aid of fluorescence and a Visually Enhanced Lesion Scope) was paired with concurrent reconstruction using a nasolabial fold flap to cover a large osteonecrosis lesion.

Utilizing Nasolabial Local Flap in Management Proliferative MRONJ: A Case Report

“…In conclusion, this report is additive evidence to the literature that confirm the Nasolabial flap is a good less aggressive option that worth to be incorporated in the management of soft tissue pathology in the area of vestibule and floor of the mouth [1]. In condition that be placed on healthy bone for successful result.…”

“…So the option for surgical resection of the total necrotic bone with safety margin with good soft tissue coverage is an ideal option as demonstrated in this reported case, Nasolabial flap is myocutaneous pedicled flap with good blood supply derived from the facial artery. It is simple easy surgical intervention that does not cause high morbidity or aesthetic disfigurement [1].…”

“…Medication-related osteonecrosis of the jaw (MRONJ) is dehiscence of maxillofacial bone resulted as a consequence of drug therapy [1]. The exact pathophysiology of MRONJ is not clearly understood and.…”