Nasogastric Administration of Omeprazole

Elliott, Rohan A

doi:10.1002/jppr1998283174

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2008

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“…Dispersible tablets are an option but cannot be used via fine bore tubes. 4,5 An audit at the Sydney Children's Hospital found that around 9% of all inpatients were prescribed omeprazole and 85% needed a liquid formulation. 6 The Sydney Children's Hospital pharmacy department prepares 12 L of omeprazole liquid formulation per month and the Royal Children's Hospital, Melbourne prepares 2 L of omeprazole suspension each working day.…”

Section: Introductionmentioning

confidence: 99%

Stability of Omeprazole Mixtures: Implications for Paediatric Prescribing

Graudins

Kivi

Tattam

2008

Pharmacy Practice and Res

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Background: Commercial omeprazole paediatric mixtures are not available. The stability of omeprazole mixtures prepared from Probitor capsules or omeprazole powder has not been established. Aim: To determine the physicochemical stability of two omeprazole mixtures, prepared from Probitor capsules or omeprazole powder BP, over a 45-day period under refrigeration or at room temperature, shaken or unshaken. Method: Omeprazole 2 mg/mL mixtures were prepared using standard procedures by either emptying the contents of Probitor capsules or by adding omeprazole powder to preserved sodium bicarbonate 8.4% solution. Each formulation was stored in 100 mL amber glass bottles under refrigeration (2-8

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Section: Introductionmentioning

confidence: 99%