Nasal septal teratoma in a child

Abstract

Background: Teratoma is a rare developmental neoplasm that arises from totipotential tumor stem cells. Head and neck teratomas constitute about 10% of all cases. Only two cases of mature teratoma of the nasal septum have previously been documented in the world literature.

Inverted Papillomas and Benign Nonneoplastic Lesions of the Nasal Cavity

“…Approximately 10% of teratomas occur in the head and neck, with the majority of these occurring in the cervical region or nasopharynx. However, they have been reported in the nasal vestibule and on the nasal septum 67,68 Rare lesions, both malignant and benign, of the nasal cavity underscore the need for excision of lesions and careful pathological review.…”

Teratoma of the nasal septum in a neonate: an endoscopic approach

“…All 3 patients underwent an external approach with lateral rhinotomy to resect the tumor. Follow-ups at 3 years were free of recurrence [5,8,9].…”

“…The other cases of nasal septum teratomas include a Japanese male [8], delivered by cesarean delivery because of multiple fetal anomalies at 33 weeks of gestational age; a 19-year-old Indian male [9]; and an 18-month-old Nigerian female [5]. Symptoms included unilateral occlusion of the nose and rhinorrhea.…”

“…In contrast, teratomas of the nose or the paranasal sinus are an "extremely rare exception" [6]. Of all teratomas, 2% develop in the head and neck region [2,3,5]. The incidence of malignancy for teratomas of the head and neck region is estimated to be approximately 5% [3,7].…”

“…Commonly, teratomas of the head and neck are located in the thyroid gland, palate, or nasopharynx [2,3,5]. In contrast, teratomas of the nose or the paranasal sinus are an "extremely rare exception" [6].…”