Nasal resistances are useful in identifying children with severe obstructive sleep apnea before polysomnography

Rizzi, Maurizio; Onorato, J.; Andreoli, A.; Colombo, Stefano; Pecis, Marica; Marchisio, Paola; Morelli, Marco Bruno; Principi, Nicola; Esposito, Susanna; Sergi, Maria Chiara

doi:10.1016/s0165-5876(02)00119-2

Cited by 46 publications

(30 citation statements)

References 29 publications

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“…In subject OSAS 1, the transnasal resistance was 0.48 kPa/L/s at 150 Pa nasal pressure drops, which is consistent with the published measurements. The model is also consistent with a clinical study showing that nasal resistance is higher in children with OSAS than in normal subjects (Rizzi et al, 2002).…”

Section: Article In Presssupporting

confidence: 89%

Computational fluid dynamics modeling of the upper airway of children with obstructive sleep apnea syndrome in steady flow

Chun

Sin

McDonough

et al. 2006

Journal of Biomechanics

149

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Section: Article In Presssupporting

confidence: 89%

Computational fluid dynamics modeling of the upper airway of children with obstructive sleep apnea syndrome in steady flow

Chun

Sin

McDonough

et al. 2006

Journal of Biomechanics

149

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“…29 Chronic exposures to allergens and/or irritants may augment upper airway inflammation, increasing nasal resistance, and perhaps triggering lymphoid hypertrophy and pharyngeal obstruction. 30,31 Additionally, children from low SES neighborhoods may experience greater exposure to toxins such as lead 26 and environmental contaminants from toxic waste sites and active or former industrial sites. 32 Although speculative, early life exposures to environmental neurotoxins may adversely influence neuromuscular function of the upper airway.…”

Section: Discussionmentioning

confidence: 99%

Neighborhood disadvantage as a risk factor for pediatric obstructive sleep apnea

Spilsbury

Storfer‐Isser

Kirchner

et al. 2006

The Journal of Pediatrics

214

169

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“…90 One uncontrolled study (level IV) showed that nasal resistance, as measured by using rhinometry, had a high sensitivity and specificity for predicting polysomnographic OSAS. 91 This technique warrants further study and validation.…”

Section: Radiologic Studiesmentioning

confidence: 94%

Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome

Marcus¹,

Brooks²,

Ward³

et al. 2012

Pediatrics

1,468

1,504

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OBJECTIVE: This technical report describes the procedures involved in developing recommendations on the management of childhood obstructive sleep apnea syndrome (OSAS). METHODS: The literature from 1999 through 2011 was evaluated. RESULTS AND CONCLUSIONS: A total of 3166 titles were reviewed, of which 350 provided relevant data. Most articles were level II through IV. The prevalence of OSAS ranged from 0% to 5.7%, with obesity being an independent risk factor. OSAS was associated with cardiovascular, growth, and neurobehavioral abnormalities and possibly inflammation. Most diagnostic screening tests had low sensitivity and specificity. Treatment of OSAS resulted in improvements in behavior and attention and likely improvement in cognitive abilities. Primary treatment is adenotonsillectomy (AT). Data were insufficient to recommend specific surgical techniques; however, children undergoing partial tonsillectomy should be monitored for possible recurrence of OSAS. Although OSAS improved postoperatively, the proportion of patients who had residual OSAS ranged from 13% to 29% in low-risk populations to 73% when obese children were included and stricter polysomnographic criteria were used. Nevertheless, OSAS may improve after AT even in obese children, thus supporting surgery as a reasonable initial treatment. A significant number of obese patients required intubation or continuous positive airway pressure (CPAP) postoperatively, which reinforces the need for inpatient observation. CPAP was effective in the treatment of OSAS, but adherence is a major barrier. For this reason, CPAP is not recommended as first-line therapy for OSAS when AT is an option. Intranasal steroids may ameliorate mild OSAS, but follow-up is needed. Data were insufficient to recommend rapid maxillary expansion.

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Nasal resistances are useful in identifying children with severe obstructive sleep apnea before polysomnography

Cited by 46 publications

References 29 publications

Computational fluid dynamics modeling of the upper airway of children with obstructive sleep apnea syndrome in steady flow

Computational fluid dynamics modeling of the upper airway of children with obstructive sleep apnea syndrome in steady flow

Neighborhood disadvantage as a risk factor for pediatric obstructive sleep apnea

Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome

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