Nasal Polyps and Rhinosinusitis

Huvenne, Wouter; Cauwenberge, Paul Van; Bachert, Claus

doi:10.1002/9781444300918.ch70

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2010

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“…Enterotoxins of Staphylococcus aureus have been implicated in the pathology of chronic airway inflammation, as IgE directed against Staphylococcus aureus enterotoxins (SAE) was found in chronic upper airway inflammation [14–16]. These SAE act as superantigens as they potentially activate T cells via the linkage of the β chain of the T cell receptor (TCR) to MHC class II molecules on antigen‐presenting cells (APC) outside the peptide‐binding groove area [17].…”

Section: Introductionmentioning

confidence: 99%