Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation

Davis, Peter G; Lemyre, Brigitte; Paoli, Antonio G De

doi:10.1002/14651858.cd003212

Cited by 132 publications

(80 citation statements)

References 14 publications

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“…1,6,7,11,19 Barrington et al and Davis et al were unanimous in affirming that nIPPV is a useful and effective method to increase the benefits of nCPAP in the prevention of extubation failure of premature infants in the first hours after extubation. 1, 8 Likewise, Khalaf et al consider nIPPV as more effective than nCPAP in the weaning of premature infants with respiratory distress syndrome (RDS) using mechanical ventilation, and recommend that nIPPV should be used as the primary extubation method even in premature infants with impaired pulmonary function. 6 Kahramaner et al also concluded that nIPPV has a better effect than nCPAP after extubation of premature infants, as it reduced the occurrence of atelectasis, the need for re-intubation and even the number of deaths.…”

Section: Discussionmentioning

confidence: 99%

“…These interventions include the use of nasal continuous positive airway pressure (nCPAP), 8,9 which has also demonstrated extubation failure at around 28% in newborns, which justifies the development and/or improvement of methods to increase its efficacy. 9 A new non-invasive, nasal method known as nasal intermittent positive pressure ventilation (nIPPV) has been used in extubated premature infants in order to decrease the incidence of extubation failure.…”

Section: Introductionmentioning

confidence: 99%

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Randomized controlled trial comparing nasal intermittent positive pressure ventilation and nasal continuous positive airway pressure in premature infants after tracheal extubation

Komatsu

Diniz

Ferraro

et al. 2016

Rev. Assoc. Med. Bras.

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Objective:To analyze the frequency of extubation failure in premature infants using conventional mechanical ventilation (MV) after extubation in groups subjected to nasal intermittent positive pressure ventilation (nIPPV) and continuous positive airway pressure (nCPAP). Method: Seventy-two premature infants with respiratory failure were studied, with a gestational age (GA) ≤ 36 weeks and birth weight (BW) > 750 g, who required tracheal intubation and mechanical ventilation. The study was controlled and randomized in order to ensure that the members of the groups used in the research were chosen at random. Randomization was performed at the time of extubation using sealed envelopes. Extubation failure was defined as the need for re-intubation and mechanical ventilation during the first 72 hours after extubation. Results: Among the 36 premature infants randomized to nIPPV, six (16.6%) presented extubation failure in comparison to 11 (30.5%) of the 36 premature infants randomized to nCPAP. There was no statistical difference between the two study groups regarding BW, GA, classification of the premature infant, and MV time. The main cause of extubation failure was the occurrence of apnea. Gastrointestinal and neurological complications did not occur in the premature infants participating in the study. Conclusion: We found that, despite the extubation failure of the group of premature infants submitted to nIPPV being numerically smaller than in premature infants submitted to nCPAP, there was no statistically significant difference between the two modes of ventilatory support after extubation.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Randomized controlled trial comparing nasal intermittent positive pressure ventilation and nasal continuous positive airway pressure in premature infants after tracheal extubation

Komatsu

Diniz

Ferraro

et al. 2016

Rev. Assoc. Med. Bras.

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show abstract

“…Atualmente, as maiores evidências científicas para a aplicação de VPPIN referem-se ao suporte para reduzir taxas de reintubação e evitar episódios de apneia 24,26,27 . As indicações ao uso de VPPIN mais citadas pelas unidades do Nordeste foram o período pós-extubação (79,7%) e durante episódios de apneia (78,3%).…”

Section: Discussionunclassified

Practices of use of nasal intermittent positive pressure ventilation (NIPPV) in neonatology in northeastern Brazil

Medeiros¹,

Carvalho²,

Soriano³

2012

J Pediatr (Rio J)

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Objective: To investigate the use of nasal intermittent positive pressure ventilation (NIPPV) in level three neonatal intensive care units (NICU) in northeastern Brazil. Methods:This observational cross-sectional survey was conducted from March 2009 to January 2010 in all level three NICUs in northeastern Brazil that are registered in the Brazilian Registry of Health Establishments (Cadastro Nacional de Estabelecimentos de Saúde, CNES) of the Ministry of Health. Questionnaires about the use of NIPPV were sent to the NICU directors in each institution. Statistical analysis was conducted using the software Epi-Info 6.04 and double data entry. A chi-square test was used to compare variables, and the level of statistical significance was set at p ≤ 0.05. Results: This study identified 93 level three NICUs in northeasternBrazil registered in CNES, and 87% answered the study questionnaire. ResumoObjetivo: Conhecer as práticas referentes ao uso de ventilação por pressão positiva intermitente nasal (VPPIN) em unidades terciárias de atendimento neonatal do Nordeste brasileiro.Métodos: Estudo observacional seccional tipo inquérito, realizado entre março de 2009 e janeiro de 2010 em todas as instituições de atendimento neonatal de nível terciário localizadas no Nordeste brasileiro, cadastradas no Conselho Nacional dos Estabelecimentos de Saúde (CNES) do Ministério de Saúde. Realizado por meio de levantamento, utilizando questionários sobre o uso de VPPIN, enviados aos responsáveis das unidades de cuidados intensivos neonatais de cada instituição. A análise estatística foi realizada pelo software Epi-Info versão 6.04, com dupla entrada de dados. As variáveis foram comparadas pelo teste do qui-quadrado, sendo considerado nível de significância de 5%.Resultados: Estão cadastradas no CNES 93 unidades terciárias neonatais no Nordeste brasileiro. Os questionários foram respondidos por 87% delas. A maior parte classificou-se como de natureza privada (30,7%) ou pública estadual (29,4%). O número de instituições que se utilizam da VPPIN correspondeu a 98,7% do total. Grande parte das unidades (92,8 %) declarou utilizar aparelhos de ventilação pulmonar mecânica, adaptados para aplicação de VPPIN, e pronga binasal curta como interface (94,2%). O protocolo para aplicação de VPPIN existia em apenas 17,3% das unidades. A média dos valores de pressão positiva inspiratória adotados foi de 20,0 cmH 2 O (desvio padrão = 4,47) e de pressão expiratória final positiva foi de 5,0 cmH 2 O (desvio padrão = 0,84). Conclusão:A VPPIN representa um suporte utilizado pelas unidades neonatais no Nordeste brasileiro, embora se observe pouca uniformização quanto às indicações e parâmetros adotados entre as instituições. J Pediatr (Rio J). 2012;88(1):48-53:Respiração artificial, neonatologia, unidade de terapia intensiva, recém-nascido. Practices of use of nasal intermittent positive pressure ventilation (NIPPV) in neonatology in northeastern Brazil

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“…The Cochrane Review of the use of NIPPV has suggested that future trials should enroll sufficient numbers to detect differences in important outcomes such as BPD. 28 There are at least two ongoing RCT looking at BPD and death as outcomes (NIPPV in premature infants; Clinicaltrials.gov NCT00433212; NIPPV in newborn infants with RDS; Clinicaltrials.gov NCT00780624).…”

Section: Strategizing (S)nippvmentioning

confidence: 99%

Nasal intermittent positive pressure ventilation in the newborn: review of literature and evidence-based guidelines

Bhandari

2009

J Perinatol

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Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation

Cited by 132 publications

References 14 publications

Randomized controlled trial comparing nasal intermittent positive pressure ventilation and nasal continuous positive airway pressure in premature infants after tracheal extubation

Randomized controlled trial comparing nasal intermittent positive pressure ventilation and nasal continuous positive airway pressure in premature infants after tracheal extubation

Practices of use of nasal intermittent positive pressure ventilation (NIPPV) in neonatology in northeastern Brazil

Nasal intermittent positive pressure ventilation in the newborn: review of literature and evidence-based guidelines

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