Nasal hygiene in patients with end-stage renal disease

Abstract

Staphylococcus aureus is the most common endogenous infection in patients with end-stage renal disease (ESRD), and the anterior nares are the most common endogenous S. aureus carrier sites. Eliminating nasal S. aureus will greatly benefit ESRD patients. However, prophylactic topical nasal usage of mupirocin or any kind of antibiotic is against the principles of antibiotic usage. Nasal irrigation has been demonstrated to significantly increase ciliary clearance and decrease mucous inflammation, and has been proven to be an inexpensive, effective, simple, and safe treatment method in nasal health care. We propose that nasal irrigation might be the appropriate nasal hygiene intervention for ESRD patients and should be routinely applied in ESRD patients, especially those with risk factors.

Association between Chronic Kidney Disease and Chronic Rhinosinusitis: A Longitudinal Follow-Up Study Using a National Health Screening Cohort

“…Recent studies have indicated a potential connection between CKD and sinonasal conditions, such as epistaxis, infections, and olfactory dysfunction [ 13 , 14 , 15 ]. However, only a few studies have assessed the direct association between CKD and CRS.…”