2021
DOI: 10.1097/spc.0000000000000566
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Nasal high flow oxygen therapy during acute admissions or periods of worsening symptoms

Abstract: Purpose of reviewNasal high flow therapy (NHF) is increasingly used in acute care settings. In this review, we consider recent advances in the utilization of NHF in chronic obstructive pulmonary disease (COPD), terminal cancer and symptom management. Considerations around NHF use during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic are also discussed.Recent findingsNHF enables humidification and high flows to be provided together with titrated, supplemental oxygen therapy. Compared … Show more

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Cited by 2 publications
(3 citation statements)
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References 74 publications
(118 reference statements)
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“…B. Opioide bei Atemnot, Haloperidol bei Übelkeit, Butylscopolamin bei terminaler Rasselatmung) auch maschinelle Unterstützungsmöglichkeiten (z. B. nichtinvasive Beatmung oder High-flow-Sauerstofftherapie) infrage [ 42 , 43 ]. Sollte keine effektive Symptomlinderung gelingen, steht auch die Möglichkeit der gezielten Sedierung am Lebensende (z.…”
Section: Bausteine Der Palliativmedizin In Der Klinischen Notfall- Un...unclassified
“…B. Opioide bei Atemnot, Haloperidol bei Übelkeit, Butylscopolamin bei terminaler Rasselatmung) auch maschinelle Unterstützungsmöglichkeiten (z. B. nichtinvasive Beatmung oder High-flow-Sauerstofftherapie) infrage [ 42 , 43 ]. Sollte keine effektive Symptomlinderung gelingen, steht auch die Möglichkeit der gezielten Sedierung am Lebensende (z.…”
Section: Bausteine Der Palliativmedizin In Der Klinischen Notfall- Un...unclassified
“…Nasal high flow (NHF) oxygen therapy has emerged as an important method to provide titrated and more efficient oxygen supplementation, as reviewed by Munsif et al [2]. Advantages include the provision of warm, humidified gas (compared to the cold and dry oxygen of regular low flow therapy) which can improve patient comfort and adherence, as well as the opportunity to use much higher flow rates which can 'wash out' dead space and decrease carbon dioxide retention.…”
mentioning
confidence: 99%
“…The net clinical benefit between these advantages and potential adverse effects are discussed by the authors to inform improved management of worsening respiratory failure and symptoms. Of note, high flow oxygen therapy has limited evidence for treating acute hypercapnic respiratory failure, with significant alveolar hypoventilation, where the first-line treatment is noninvasive ventilation (NIV) [2].…”
mentioning
confidence: 99%