Nasal glial heterotopia in children: Two case reports and literature review

Yan, Yang-yan; Zhou, Zhiying; Bi, Jing; Fu, Yong

doi:10.1016/j.ijporl.2019.109728

Cited by 15 publications

(16 citation statements)

References 6 publications

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“…However, early surgical treatment is advocated because continued gliosis may lead to deformity and facial bone erosion 17 . NGH requires multidisciplinary management but has a good prognosis 18 . Transnasal endoscopic surgery is recommended for patients with intranasal glial heterotopia.…”

Section: Discussionmentioning

confidence: 99%

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Intranasal glial heterotopia in an infant boy

Zhang

Tang

2021

Pediatric Investigation

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Introduction Nasal glial heterotopia is a rare congenital developmental disorder characterized by meningeal epithelium and/or glial components. Case presentation A 2‐month‐old boy presented for treatment of a congenital mass in the right nasal cavity near the pharynx. The preoperative diagnosis was congenital intranasal neoplasm. Nasal endoscopic resection of the nasopharyngeal mass was performed under general anesthesia. Histological findings in the resected tissue supported a diagnosis of intranasal glial heterotopia. The surgical outcome was good and no surgical site infection occurred. During 1 year of follow‐up, the patient did not exhibit recurrence of heterotopia or related symptoms. Conclusion Transnasal endoscopic surgery is recommended for patients with intranasal glial heterotopia. Thorough preoperative imaging should be performed before glioma resection. The mass should be differentiated from encephalocele to prevent cerebrospinal fluid leakage and meningitis.

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Section: Discussionmentioning

confidence: 99%

“…17 NGH requires multidisciplinary management but has a good prognosis. 18 Transnasal endoscopic surgery is recommended for patients with intranasal glial heterotopia. Due to advances in endoscopic equipment and technology, intranasal glial heterotopias can now be properly exposed and completely removed.…”

Section: Figurementioning

confidence: 99%

Intranasal glial heterotopia in an infant boy

Zhang

Tang

2021

Pediatric Investigation

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“…4 Postoperative radiological follow-up is fundamental because the recurrence rate has been reported as 4%-10%. 5 NGH is treated by surgical resection because of the increasing volume of the mass and the risk of infection. Craniotomy was more frequently used in the past but is now indicated only for intracranial extension.…”

Section: Descriptionmentioning

confidence: 99%

Diagnosis and treatment of congenital nasal glioma

et al. 2021

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“…The incidence of congenital nasal masses is reportedly 1 in 20,000-40,000 live births 1 , 2 , and nasal glial heterotopia (NGH) accounts for approximately 5% of them 3 . Since the nose and nasopharynx are the most commonly involved areas, NGH is also known as nasal glioma 4 . Other affected sites include ear, face, neck and orbit.…”

Section: Introductionmentioning

confidence: 99%

“…Due to the rarity of this entity, its diagnosis can be delayed and the diagnostic tools, treatment options and follow-up may be unclear. Although some reviews exist, they are neither systematic or complete 4 , 11 . We present a case report and the first systematic review of all reported NGH.…”

Section: Introductionmentioning

confidence: 99%

Nasal glial heterotopia: a systematic review of the literature and case report

Gállego

Menter

Guertler

et al. 2022

Acta Otorhinolaryngol Ital

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SUMMARY Nasal glial heterotopia (NGH) is a rare congenital, non-neoplastic displacement of cerebral tissue in extracranial sites. Together with a case report of NGH, we present the first systematic review of all published cases in order to summarise the relevant clinical findings and appropriate therapy, making the available evidence accessible to decision makers. A total of 72 original publications including 152 NGH cases were identified. The male:female ratio was 3:2. Most patients were children under 18 years (130 patients) and only 8% of cases were diagnosed in adults. The main clinical presentation forms were asymptomatic masses around the nasal root as well as nasal congestion. Magnetic resonance imaging was performed in 39% of patients, computed tomography in 22% of patients and a combination of both in 20% of patients. A diagnostic biopsy was performed in only 7 patients. All patients underwent surgical treatment and recurrence was reported in 14 patients within the first year of follow-up. In conclusion, NGH should be considered as a differential diagnosis of nasal masses in children. MRI is mandatory in order to exclude a connection to the central nervous system. Complete resection is curative treatment.

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Nasal glial heterotopia in children: Two case reports and literature review

Cited by 15 publications

References 6 publications

Intranasal glial heterotopia in an infant boy

Intranasal glial heterotopia in an infant boy

Diagnosis and treatment of congenital nasal glioma

Nasal glial heterotopia: a systematic review of the literature and case report

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