Nasal carriage of methicillin-resistant Staphylococcus aureus in university students

Prates, Karina Aparecida; Torres, Ana; Garcia, Lourdes Botelho; Ogatta, Sueli Fumie Yamada; Cardoso, Celso Luíz; Tognim, Maria Cristina Bronharo

doi:10.1016/s1413-8670(10)70064-7

Cited by 35 publications

(25 citation statements)

References 17 publications

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“…None of the isolates were multidrug resistant in the present study unlike Goyal et al who reported 30% (3/10) resistance to all the antibiotics tested [26, 27]. It is alarming to note that 60% (6/10) isolates were resistant to ciprofloxacin since it had been proposed as an alternative for treatment of MRSA infection [28]. Increasing number of resistant strains may be the result of selection pressure owing to uncontrolled drug usage in the community.…”

Section: Discussioncontrasting

confidence: 57%

Staphylococcus aureus: Screening for Nasal Carriers in a Community Setting with Special Reference to MRSA

et al. 2014

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Introduction. Emergence of MRSA infections among previously healthy persons in community settings (without exposure to health care facilities) has been noted recently. MRSA infections are now classified as health care-associated MRSA (HA-MRSA) and community-associated MRSA (CA-MRSA) infections. Its colonization is an important risk factor for subsequent MRSA infection. Aims and Objectives. The aim was to screen patients and health care workers for staphylococcal carriage, identify risk factors for MRSA colonization, and determine the sensitivity pattern. Materials and Methods. A total of 200 subjects were screened for nasal carriage after obtaining verbal consent. These were both healthy subjects attending various outpatient departments and health care workers. Specimens were collected from the anterior nares using premoistened sterile cotton swabs and inoculated onto blood agar and mannitol salt agar and incubated at 37°C for 24–48 h. Results. Staphylococcus aureus colonisation was found to be 12% (n = 24). MRSA was identified in 5% (n = 10) which represents 41.66% of SA. A total of 10 strains of MRSA were isolated from 200 subjects, giving an overall positivity rate of 5%. Discussion. Staphylococcal colonization was found to be 12% (MRSA 5%). Fluoroquinolone resistance was remarkable whereas all strains were sensitive to vancomycin, teicoplanin, linezolid, quinupristin-dalfopristin.

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Section: Discussioncontrasting

confidence: 57%

Staphylococcus aureus: Screening for Nasal Carriers in a Community Setting with Special Reference to MRSA

et al. 2014

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“…Karina et al conducted a similar study among the medical students in Brazil and observed a percentage of nasal Staphylococcus aureus isolation of 40.8%. 24 In our study the nasal Staphylococcus aureus isolation was 21%. Samie et al conducted a similar study on biofilm and beta-lactamase detection using similar methods and detected 42 % were biofilm producers among which 16% were beta-lactamase positive.…”

Section: Discussionsupporting

confidence: 44%

“…All the beta-lactamase producers were resistant for Penicillin and Ampicillin but showed 100% sensitivity to Vancomycin corresponding with the earlier reports. 24 There is a possibility of transmission of these virulence factors from the healthy individuals to those at high risk such as patients on long term catheterization, or having indwelling devices in a medical set up, which may be difficult to treat with the commonly available antimicrobial agents.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of biofilm and beta-lactamase producing Staphylococcus in nasal and throat isolates from healthy volunteers: A medical alert

et al. 2015

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Background: The Staphylococci species are the predominant inhabitants of the nose and throat as normal flora, they are now becoming a threat due to their capacity to produce biofilm. Biofilm related infections are difficult to be treated unless it is diagnosed early. The aim was to study the prevalence of biofilm and beta-lactamase production in Staphylococcus isolates from nasal and throat mucosa in healthy volunteers.Methods: Staphlococcal isolates were collected from nasal and throat swabs of 100 healthy volunteers at Gulf Medical University and Gulf Medical College Hospital, Ajman, UAE. Staphylococcus aureus or Coagulase Negative Staphylococcus (CoNS) was classified from growth on Mannitol Salt Agar and tube coagulase test. Biofilm production detected by Christensen’s tissue culture plate and Congo red agar methods. Betalactamase production among biofilm producers identified by iodometric tube method.Results: Among 100 Staphylococcus isolates, 41 were Staphylococcus aureus of which 61% were biofilm producers of which 46.3% were betalactamase positive. Among the 59 CoNS isolates, 64.4% were biofilm producers of which 30.5% were beta-lactamase positive. Predominance of nasal Staphylococcal isolation observed among males at the age group of <20 years.Conclusion: Biofilm-producing Staphylococcus inhabits the nasal and throat mucosa of healthy individuals. Beta-lactamase production was higher in Staphylococcus aureus positive for biofilm producers as compared to CoNS. Transmission of these biofilm producers with drug resistance factors from the healthy individuals to high risk patients with indwelling devices need to be considered.Nepal Journal of Medical Sciences Vol.3(2) 2014: 79-83

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“…Epidemiological studies conducted in Latin American hospitals report a prevalence of S. aureus colonization from 20 to 60% in health area students [ 10 – 13 ], with an important presence of MRSA strains in higher percentage than in Europe [ 14 – 16 ].…”

Section: Introductionmentioning

confidence: 99%

Characterization ofStaphylococcus aureusIsolates That Colonize Medical Students in a Hospital of the City of Cali, Colombia

Marín

Arciniegas

Vivas

2015

International Journal of Microbiology

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Introduction. Nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) represents a risk for the spread of bacteria. This study characterized the S. aureus isolated from medical students, who were in their clinical rotation at a hospital in the city of Cali. Materials and Methods. 216 students participated in the study and 63 isolates of S. aureus were evaluated for susceptibility and PCR amplification of agr and mecA genes. The origin of MRSA isolates was established by analyzing agr polymorphisms. Results. A total of 29.2% of students were colonized by S. aureus and nasal carriage rate was 23.6% and 14.3% MRSA. Three agr groups (agr II, and agr III) were identified; the agr I group was the most common, with a 35% prevalence; this group is from community origin. Conclusion. The present study demonstrates that medical students carry S. aureus strains, with the threat of spreading them both to community and hospital environments.

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Nasal carriage of methicillin-resistant Staphylococcus aureus in university students

Cited by 35 publications

References 17 publications

Staphylococcus aureus: Screening for Nasal Carriers in a Community Setting with Special Reference to MRSA

Staphylococcus aureus: Screening for Nasal Carriers in a Community Setting with Special Reference to MRSA

Prevalence of biofilm and beta-lactamase producing Staphylococcus in nasal and throat isolates from healthy volunteers: A medical alert

Characterization ofStaphylococcus aureusIsolates That Colonize Medical Students in a Hospital of the City of Cali, Colombia

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