Nasal Carriage of 200 Patients with Nasal Bone Fracture in Korea

Lee, Jun Wook; Kim, Young-Joon; Kim, Hoon; Nam, Sang Hyun; Shin, Bo Moon; Choi, Young Back

doi:10.5999/aps.2013.40.5.536

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…The incidence of surgical site infections in nasal surgeries is extremely rare [12,14,15]; however, mucosal barrier violation and intranasal packing during surgery may lead to infectious complications as a result of bacteremia (e.g., toxic shock syndrome, endocarditis, and meningitis) [12][13][14][15]. Hence, the benefits of antibiotic prophylaxis may outweigh its potential deleterious effects, including allergic reactions, increased medical costs, and the emergence of antibiotic resistance.…”

Section: Archives Of Craniofacial Surgerymentioning

confidence: 99%

Antibiotic use in nasal bone fracture: a nationwide population-based cohort study in Korea

Jeon

Jung

Song

et al. 2021

Arch Craniofac Surg

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Background: Prophylactic antibiotics are commonly used in craniofacial surgeries. Despite the low risk of surgical site infection after nasal surgery, a lack of consensus regarding the use of antibiotic prophylaxis in the closed reduction of nasal bone fractures has led to inappropriate prescribing patterns. Through this study, we aimed to investigate the status of prophylactic antibiotic use in closed reductions of nasal bone fractures in Korea.Methods: This retrospective cohort study was conducted using data from the National Health Insurance Service-National Sample Cohort of Korea from 2005 to 2015. We analyzed the medical records of patients who underwent closed reduction of nasal bone fractures. The sex, age, region of residence, comorbidities, and socioeconomic variables of the patients were collected from the database. Factors that affect the prescription of perioperative antibiotics were evaluated using multivariate logistic regression analysis.Results: A total of 3,678 patients (mean±standard deviation of age, 28.7±14.9 years; 2,850 men [77.5%]; 828 women [22.5%]) were included in this study. The rate of antibiotic prescription during the perioperative period was 51.4%. Approximately 68.8% of prescriptions were written for patients who had received general anesthesia. The odds of perioperative prophylactic antibiotic use were significantly higher in patients who received general anesthesia than who received local anesthesia (odds ratio, 1.59). No difference was found in terms of patient age and physician specialty. Second-generation cephalosporins were the most commonly prescribed antibiotic (45.3%), followed by third- and first-generation cephalosporins (20.3% and 18.8%, respectively). In contrast, lincomycin derivatives and aminoglycosides were not prescribed.Conclusion: The findings of this study showed that there was a wide variety of perioperative antibiotic prescription patterns used in nasal bone surgeries. Evidence-based guidance regarding the prescribing of antimicrobial agents for the closed reduction of nasal bone fractures should be considered in future research.

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