Nasal angiomyolipoma causing persistent nasal congestion

Suresh, Rishi; Liu, Lina; Clark, David W.

doi:10.1080/08998280.2020.1772029

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…Only 5 similar cases had previously been reported. [1][2][3][4][5] Angiomyolipoma represents a part of the group of perivascular epithelioid cell tumors (PEComas) including histologically similar lesions occurring in a variety of cutaneous, visceral, and soft tissue sites. 6 Although angiomyolipoma is a benign lesion, there is evidence in the literature of malignant transformation of angiomyolipoma primarily localized in the kidney and liver.…”

Section: Discussionmentioning

confidence: 99%

“…9,10 About 80% of patients with nasal angiomyolipoma are male and between 29 and 88 years of age. [1][2][3][4][5] Watanabe and Suzuki proposed the classification of angiomyolipomas into 2 clinicopathological types: the mucocutaneous type, originating from the skin, nasal cavity, oropharynx, and larynx, and the hepatorenal (PEComatous) type. 11 Histopathologically, the mucocutaneous type is composed of spindled and mature smooth muscle cells, has no epithelioid morphology, and, as was the case with our patient's tumor demonstrates no immunoreactivity to the melanocytic marker HMB-45.…”

Section: Discussionmentioning

confidence: 99%

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Angiomyolipoma Originating From the Nasal Vestibule: A Case Report

et al. 2021

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Angiomyolipoma is a benign, mesenchymal, hamartomatous lesion often described in the kidney and may be associated with tuberous sclerosis. Nasal angiomyolipoma is an extremely rare tumor with fewer than 20 cases reported in the literature. We report a case of angiomyolipoma arising in the right nasal vestibule in a 68-year-old male with mild, recurrent right-sided epistaxis, and nasal obstruction. With the exception of arterial hypertension, the patient did not have any comorbidities. Gross examination showed a well-circumscribed, lobulated mass. On the microscopic level, it was composed of mature smooth muscle cells, thick-walled blood vessels of varying sizes, and islands of mature adipose tissue. Angiomyolipoma should be considered as a differential diagnosis for unilateral nasal masses, especially those situated in the nasal vestibule.

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