Narrowband ultraviolet B radiation therapy for recalcitrant vitiligo in Asians

Role of oxidative stress in the pathogenesis of vitiligo with special emphasis on the antioxidant action of narrowband ultraviolet B phototherapy

“…1,4,[24][25][26] In this regard, a lower likelihood of erythema and xerosis development, carcinogenic effects and a lack of oral treatment obligation were reported advantages of NB-UVB phototherapy when compared with PUVA. 27 Considering the mechanism of action of phototherapy, while failing to achieve complete normalization of levels of oxidantantioxidant markers compared with control levels, the use of NB-UVB phototherapy for 6 months in the present study was associated with significant improvement in oxidantantioxidant imbalance, shown by reduction in MDA levels and an increase in GSH-Px levels.…”

Efficacy, predictors of response, and long-term follow-up in patients with vitiligo treated with narrowband UVB phototherapy

“…Several studies have been published reporting its efficacy in different populations. [2][3][4][5][6][7][8][9][10][11][12][13][14] In the current study, 34.4% of patients with lesions on the face and 7.4% of patients with lesions on the body achieved cosmetically acceptable repigmentation after up to 1.5 years of treatment (P \ .0046). Many studies have reported better results for the face in comparison with the body.…”

“…1 Since the first report by Westerhof and Nieuweboer-Krobotova, 2 several studies have been published on the treatment of vitiligo with NB-UVB in different populations with variable results. [3][4][5][6][7][8][9][10][11][12][13][14] More than 75% repigmentation has been achieved by 12.5% 12 to 75% 9 of treated patients, after approximately 1 year of treatment. Taking into consideration that NB-UVB is an office-based treatment that may require more than 1 year for its completion, it is important to be able to identify before treatment the patients who are going to benefit more and to provide them with an estimation of the stability of the induced repigmentation.…”

Current Approach to Phototherapy Applications in Dermatology Practice: Part 2. Phototherapy in Vitiligo, Mycosis Fungoides, Atopic Dermatitis, Sclerosing Diseases and Psoriasis

“…Yirmi beş hastanın dört yıla kadar izlendiği bir çalışmada bir yıl içindeki relaps oranı %44 (12), dokuz hastanın iki yıla kadar izlendiği bir çalışmada ise 18. ayda relaps oranı %43 olarak saptanmıştır (13). Buna karşılık, 150 hastanın tedavi edildiği bir çalışmada altı aylık izlem süresi içinde sadece üç hastada relaps gözlenmiştir (14).…”