Narrow‐band ultraviolet B (TL‐01) phototherapy is an effective and safe treatment option for patients with severe seborrhoeic dermatitis

Pirkhammer, D; Seeber, A.; Hönigsmann, Herbert; Tanew, Adrian

doi:10.1046/j.1365-2133.2000.03828.x

Cited by 68 publications

(30 citation statements)

References 17 publications

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“…In small open prospective trials, it has been demonstrated that NB UVB is probably effective in diseases such as lichen planus, seborrheic dermatitis, and pruritus associated with polycythemia vera. Although itch appears to be one of the most responsive subjective symptoms to NB UVB, 12,31,33,35 there is a lack of well-designed studies on patients with pruritus associated with systemic diseases, in particular comparing BB UVB with NB UVB. Possibly NB UVB is also an effective, in particular potentially itch-reducing, therapeutic option for patients with chronic urticaria or acquired perforating dermatosis.…”

Section: Study Design Methodology and Efficacymentioning

confidence: 98%

“…The condition frequently improves on sun exposure, and previous studies have documented the beneficial effect of treatment with artificial light sources including selective UVB and oral PUVA. 48 Recently Pirkhammer et al 35 reported in an open prospective study on 18 patients with severe seborrheic dermatitis (including 7 patients with lesions on the chest) who responded favorably to NB UVB 3 times weekly after a median number of 23 exposures resulting in median cumulative NB UVB dose of 9.8 J/cm 2 . The median clinical score decreased from 7.5 at baseline to 0.5 (P = .005) after 8 weeks of treatment and the pruritus score from 4.5 to 0 (P = .008).…”

Section: Seborrheic Dermatitismentioning

confidence: 96%

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Narrowband UVB phototherapy in skin conditions beyond psoriasis

Gambichler

Breuckmann

Boms

et al. 2005

Journal of the American Academy of Dermatology

110

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Section: Study Design Methodology and Efficacymentioning

confidence: 98%

Section: Seborrheic Dermatitismentioning

confidence: 96%

Narrowband UVB phototherapy in skin conditions beyond psoriasis

Gambichler

Breuckmann

Boms

et al. 2005

Journal of the American Academy of Dermatology

110

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“…The systemic antifungals that are used in therapy are ketoconazole, itraconazole and terbinafine. UVB (TL-01) phototherapy has also been shown to be effective in the treatment and prophylaxis of SD [66]. …”

Section: Prophylaxismentioning

confidence: 99%

Etiology and Management of Seborrheic Dermatitis

2004

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Seborrheic dermatitis (SD) is a common dermatological disorder that varies greatly in severity between individuals and with time. The etiology of this disease is poorly understood. Early investigators focused on the role of Malassezia (previously Pityrosporum) yeasts in the development of SD. Some researchers have hypothesized that there is an immunological component to SD and that this disease is caused by an altered immune response to Malassezia yeasts. However, other researchers view this condition as the result of hyperproliferation. Both antifungal and anti-inflammatory preparations have been used to treat SD effectively and safely. The wide range of antifungal formulations available (creams, shampoos, oral drugs) provides safe, effective and flexible treatment options for SD.

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“…All patients responded to narrowband UVB. Twelve completed the study; six had complete remission and six had marked improvement [59].…”

Section: Efficacymentioning

confidence: 99%