Narrow-band ultraviolet B in childhood vitiligo: An open prospective uncontrolled study in 28 children of South India

Kumar, Y Hari Kishan; Rao, G Raghurama

doi:10.4103/2319-7250.149424

Cited by 4 publications

(3 citation statements)

References 14 publications

(31 reference statements)

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“…Pengobatan vitiligo pada masa kanakkanak harus dimulai lebih awal oleh karena respons lebih kuat pada awal penyakit. 19,20 Tabel 6. Penelitian penggunaan fototerapi pada anak dengan vitiligo.…”

Section: Efektivitas Fototerapi Pada Vitiligo Anakunclassified

Peran Fototerapi Pada Vitiligo Anak

Dharmasamitha

Adiguna

2019

MDVI

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Vitiligo adalah gangguan pigmentasi didapat yang ditandai dengan lesi putih yang tidak berpigmen pada kulit dan rambut karena kehilangan fungsi melanosit. Sekitar 50% pasien vitiligo menunjukkan awitan sebelum usia 18 tahun, sehingga seringkali menimbulkan masalah di bidang pediatrik, baik dalam diagnosis maupun tata laksana. Penegakan diagnosis vitiligo umumnya berdasarkan anamnesis dan pemeriksaan fisik, namun dapat dilakukan pemeriksaan penunjang untuk memastikan diagnosis ataupun mencari penyakit komorbiditas. Fototerapi diberikan hanya pada pasien anak dengan vitiligo yang tetap stabil dan tidak responsif terhadap terapi topikal. Terdapat beberapa perbedaan dalam hal indikasi dan dosis yang diberikan pada fototerapi anak dan dewasa. Perkembangan dan temperamen/perilaku anak harus dinilai termasuk mempertimbangkan kecemasan, ketakutan terhadap ruangan tertutup, dan kemampuan untuk tetap diam selama perawatan, sehingga penatalaksanaannya perlu perhatian khusus. Rata-rata pemberian fototerapi pada anak dapat sampai 12-24 bulan. Oleh sebab itu efek samping pemberian fototerapi jangka panjang penting disampaikan kepada orang tua.Kata kunci: anak, fototerapi, vitiligo

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Section: Efektivitas Fototerapi Pada Vitiligo Anakunclassified

Peran Fototerapi Pada Vitiligo Anak

Dharmasamitha

Adiguna

2019

MDVI

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“…It is safe and effective for youngsters, pregnant women, and lactating mothers. Eliminating erythemogenic wavelengths underneath 311 nm grants higher intensities and more exposure time, leading to extreme advantage from phototherapy with a shorter course of treatment 7 …”

Section: Introductionmentioning

confidence: 99%

“…Eliminating erythemogenic wavelengths underneath 311 nm grants higher intensities and more exposure time, leading to extreme advantage from phototherapy with a shorter course of treatment. 7 The aim of the present study is to explore the efficacy and safety of using different concentrations of ILS combined with NB-UVB phototherapy in the treatment of non-segmental vitiligo (NSV) patients.…”

Section: Introductionmentioning

confidence: 99%

The use of intralesional corticosteroid combined with narrowband ultraviolet B in vitiligo treatment: clinical, histopathologic, and histometric evaluation

et al. 2021

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Background Treatment of vitiligo with intralesional steroid (ILS) injections has shown to be successful in quite a few studies. It is a simple and safe treatment when used with caution with a better response in localized lesions. ObjectivesThe aim of the present study is to explore the efficacy and safety of using different concentrations of intralesional corticosteroid combined with NB-UVB phototherapy in the treatment of non-segmental vitiligo (NSV) patients.Methodology Twenty patients with non-segmental vitiligo were subjected to different concentrations of ILS injections (triamcinolone acetonide); that was carried out monthly for six sessions. All patients were also subjected to twice-weekly sessions of NB-UVB for 6 months. Punch biopsy was taken from each patch before and at the end of treatment sessions. Each biopsy was stained with hematoxylin and eosin (H&E), Orcein, and Masson's trichrome stains. ResultsThere was a significant difference between all groups in their repigmentation response (P = 0.017). After treatment, the epidermal thickness (histometry) was decreased (epidermal atrophy), especially with concentrations of 2.5 and 5 mg/ml of intralesional triamcinolone acetonide injection with decreased and disorganized collagen fibers. ConclusionIntralesional corticosteroid injections combined with NB-UVB showed a good and well-tolerated therapeutic option for vitiligo. The concentrations of 0.625 and 1.25 mg/ml of triamcinolone acetonide were the safest with fewer side effects and complications. However, higher concentrations of 2.5 and 5 mg/ml were more effective but with more side effects.

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Childhood Vitiligo: A Retrospective Clinico-Epidemiological Study

Ahmed

Mohammed

et al. 2020

Preprint

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Background: Vitiligo is an acquired depigmentary disorder of the skin, mucous membrane and hair follicle resulting from selective destruction of melanocytes. Aims of Study: Identify the clinico-epidemiological characteristics of childhood vitiligo. Patients and Methods: A retrospective study carried out at the dermato-venereology clinic of Salah Al-Din Hospital. A total of 120 vitiligo patients, all younger than 17 years old, were enrolled. Results: Among included patients, (40%) were male and (60%) were female (M:F=2:3). The mean age of onset was (11.5 SD 6.4 years) with (60.8%) of patients were (11-17) years old, (25%) were (6-11) years and (14.2%) were (0-5) years old. Majority of patients were from urban area (87.5%). Generalized types of vitiligo account for (56.7%) besides (22.5%), (17.5%) and (3.3%) represented focal, acrafacial and segmental vitiligo, respectively. Only (8.3%) have nail changes, presented as longitudinal ridging followed by leukonychia. Family history was positive in (37.5%) of vitiligo patients. Treatment used for vitiligo were topical corticosteroids (92.5%), topical calcineurin inhibitors (55%), NB-UVB (84.2%), and systemic steroids (30.8%). Conclusions: Majority of childhood vitiligo develops after puberty and predominantly affects female. Generalized vitiligo is the most frequent type. Atopic dermatitis is the most common associated disease.

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Narrow-band ultraviolet B in childhood vitiligo: An open prospective uncontrolled study in 28 children of South India

Cited by 4 publications

References 14 publications

Peran Fototerapi Pada Vitiligo Anak

Peran Fototerapi Pada Vitiligo Anak

The use of intralesional corticosteroid combined with narrowband ultraviolet B in vitiligo treatment: clinical, histopathologic, and histometric evaluation

Childhood Vitiligo: A Retrospective Clinico-Epidemiological Study

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