Narrow-band imaging colonoscopy—a pilot feasibility study for the detection of polyps and correlation of surface patterns with polyp histologic diagnosis

Implications of Serum 25-hydroxyvitamin D on Prevalence of Neoplastic Polyps: A Cross-Sectional Study

“…Previous studies have demonstrated no statistically significant benefit of NBI with polyp detection [24,25]. However, a recent study supports increased polyp detection and histologic correlation with NBI, therefore suggesting that this technique be considered by endoscopists in order to optimize polyp detection rate [26]. Possible confounding factors were avoided in this study due to the consistent timing of and ingested amount of prep (1 gallon Golytely), the minimal size of polyp to be removed (≥ 3 mm), minimum accepted withdrawal time of 6 minutes, mean of bowel prep scores ≤ 5 and patients with inflammatory bowel disease given the association with increased risk of colorectal carcinoma [27].…”

Therapeutic and Diagnostic Approaches in Colonoscopy

“…The reasons for missed polyps included the quality of bowel preparation, lesion characteristics (location, number, shape, and size), the endoscopist's experience, and the operator's insertion and withdrawal techniques [41][42][43][44]. Although many clinical studies, including randomized controlled trials (RCTs), have confirmed reduced missed rates in colonoscopy using NBI techniques [45][46][47][48][49][50][51][52], one recent meta-analysis revealed that there was no statistically significant difference in the rates of adenoma detection rate between NBI and WL [53], and a large-scale multicenter Japanese study did not show an improvement with NBI [54]. Moreover, another systematic review including 8 RCTs showed that NBI did not improve detection of colorectal polyps when compared to WL [55].…”

In vivo Optical Diagnosis of Polyp Histology: Can We Omit Pathological Examination of Diminutive Polyps?

“…This heterogeneity may be explained by the use of different descriptions of vascular networks. Examples are, brown blob or dense vascular network to predict neoplasia [46][47][48]; fine capillary network, dark dots, light rounds, tubular or gyrus like [49]; microvessel thickness (invisible, thin, thick) and microvessel irregularity (invisible, regular, mildly irregular, severely irregular) [50]; vascular patter intensity (weaker, the same or darker than the surrounding mucosa) [51]; fine vascular network or dilated corkscrew type vessels and abnormal branching patterns [52]; and finally, capillary pattern (CP type I: invisible or faintly visible, CP type II: capillaries elongated and thicker and CP type III: capillaries of irregular sizes, thicker and branched) [53][54][55].Other causes of heterogeneity are the use of magnification or high-resolution endoscopes since the results with the latter are not as encouraging (see section 2.2.5) [46,49,56], and finally, better results are reported by experts.…”