2021
DOI: 10.21037/apm-21-853
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Narrative review: recent advances in doll therapy for Alzheimer’s disease

Abstract: Alzheimer's disease (AD) is a severe neurodegenerative disease which impacts the quality of life in elderly patients and imposes a significant burden to families and caregivers. The prolonged life expectancy and rapidly increasing world population significantly increased the morbidity. Although it has been widely reported that the aggregation of Beta amyloid and neurofilaments is the most significant pathological change.Currently, there is no effective drug therapy for AD, and the potential risks of pharmacoth… Show more

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Cited by 5 publications
(2 citation statements)
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“…Several authors have found benefits in the use of DT, observing a decrease of negative behaviors such as agitation, aggressiveness, or erratic wandering as well as an increase in communication with the environment and independence in daily life [ 10 , 11 , 20 ]. Systematic revisions in this regard conclude that DT has positive effects on the person with dementia as long as it improves communication with the environment, alleviates the SCPD, and improves quality of life [ 21 , 22 , 23 ]. Mitchell [ 24 , 25 ] discovered an increase in commitment levels, communication, and reduction of anguish episodes in addition to the potential of DT to improve independence in daily life.…”
Section: Introductionmentioning
confidence: 99%
“…Several authors have found benefits in the use of DT, observing a decrease of negative behaviors such as agitation, aggressiveness, or erratic wandering as well as an increase in communication with the environment and independence in daily life [ 10 , 11 , 20 ]. Systematic revisions in this regard conclude that DT has positive effects on the person with dementia as long as it improves communication with the environment, alleviates the SCPD, and improves quality of life [ 21 , 22 , 23 ]. Mitchell [ 24 , 25 ] discovered an increase in commitment levels, communication, and reduction of anguish episodes in addition to the potential of DT to improve independence in daily life.…”
Section: Introductionmentioning
confidence: 99%
“…Brittain et al [2] proposed that BPSD might indicate that the patient perceives a threat that needs managing. Doll therapy (DT) is a nonpharmacological intervention, that aims at reducing the level of anxiety and agitation in patients affected by moderate to severe dementia, mostly in nursing homes [3]. Our previous studies have also found that DT can improve the wandering symptoms of dementia patients [4,5], indicating that DT can help dementia patients become calmer and further adapt to the surrounding environment, thus improving wandering.…”
Section: Introductionmentioning
confidence: 99%