Narcolepsy Type 1 in an Adolescent With Vertical-Acquired Hiv Infection - Coincidence or Potential Trigger?

Scherrer, Karin Sofia

doi:10.26226/morressier.5ad774ddd462b80296ca6837

Cited by 1 publication

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“…We took particular interest in the relationship between the narcolepsy type 2 and Herpes zoster virus infection in this case. Although there have been no reports indicating that the Herpes zoster virus could cause narcolepsy, the association between the virus infection and sleep has been mentioned in many studies [3][4][5]7]. We believed that the patient in this case Narcolepsy type 2 is related to Herpes zoster virus infection based on the following points: 1.…”

Section: Discussionmentioning

confidence: 88%

Case report: narcolepsy type 2 due to the optic nerve infection of Herpes zoster virus

Ren

et al. 2021

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Rationale: Despite the acknowledged importance of environmental risk factors in the etiology of narcolepsy, there is little research on this topic. The optic nerve infection of Herpes zoster virus as a trigger for narcolepsy has not been investigated.Patient concerns: A 63-year-old male carpenter complained of excessive daytime sleepiness (EDS) over the past 3 years.Interventions: Treated with duloxetine hydrochloride enteric dissolution capsule (Cymbalta) 120mg after breakfast and clonazepam tablets 0.5mg before sleep.Outcomes: General examination showed no abnormalities of his heart, lungs, or abdomen. Neurological examination showed no positive sign. The blood routine and biochemical examination were normal. Denied having been vaccinated against the flu or having been infected with the flu virus. He scored 17 on the Pittsburg sleep quality index, 22 on the Epworth sleepiness scale, 40 on the self-rating anxiety scale, and 69 on the self-rating depression scale. The multiple sleep latency test data showed 2 periods of sleep-onset rapid eyes movement period across 4 successive tests; the average sleep latency was 7.9 minutes, and the rapid eyes movement latency was 1.2 minutes. Treated with duloxetine hydrochloride enteric dissolution capsule (Cymbalta) 120mg after breakfast and clonazepam tablets 0.5mg before sleep, the patient’s EDS symptoms disappeared immediately. He scored 6 on the Epworth sleepiness scale. During our follow-up three months later, he remained well with no complications.Diagnosis: We diagnosed the patient with narcolepsy type 2 according to the 3rd Edition of International Classification of Sleep Disorders (ICSD-3).Conclusion: The patient suffered from EDS and was diagnosed with narcolepsy type 2. The narcolepsy type 2 was linked to viral infection of the optic nerve. Optic nerve virus infection may affect the sleep-pondering pathway.

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Section: Discussionmentioning

confidence: 88%

Case report: narcolepsy type 2 due to the optic nerve infection of Herpes zoster virus

Ren

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

Narcolepsy Type 1 in an Adolescent With Vertical-Acquired Hiv Infection - Coincidence or Potential Trigger?

Cited by 1 publication

References 2 publications

Case report: narcolepsy type 2 due to the optic nerve infection of Herpes zoster virus

Case report: narcolepsy type 2 due to the optic nerve infection of Herpes zoster virus

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