Narcolepsy, idiopathic hypersomnolence and related conditions

Quinnell, Timothy; Smith, Ian

doi:10.7861/clinmedicine.11-3-282

Cited by 7 publications

(4 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cataplexy is rarely observed in the clinic, but when it occurs, clinicians should test deep tendon reflexes as their transient absence is highly specific for the disorder. 45,46 In patients with suspected central disorders of hypersomnolence, a neurological examination should be performed to assess for the presence of a neurological disorder affecting the brainstem, thalamus, or hypothalamus.…”

Section: Physical Examinationmentioning

confidence: 99%

Excessive Daytime Sleepiness

Gandhi

Mansukhani

Silber

et al. 2021

Mayo Clinic Proceedings

View full text Add to dashboard Cite

Section: Physical Examinationmentioning

confidence: 99%

Excessive Daytime Sleepiness

Gandhi

Mansukhani

Silber

et al. 2021

Mayo Clinic Proceedings

View full text Add to dashboard Cite

Section: Sleep Hygienementioning

confidence: 99%

“…Optimal sleep hygiene for persons with narcolepsy can include sufficient hours of nighttime sleep, consistent sleepwake habits and patterns, and scheduled brief daytime naps [28][29][30] . In addition, alcohol, caffeine, tobacco, and heavy meals should be avoided several hours before bedtime 7,30 . An environment that is conducive to sleep (e.g., free of loud noise or harsh light) can also make a significant impact on sleep quality.…”

Section: Sleep Hygienementioning

confidence: 99%

Current and Future Treatment Options for Narcolepsy: A Review

Bhattarai¹,

Sumerall²

2017

Sleep Sci

View full text Add to dashboard Cite

Narcolepsy is a chronic neurological sleep disorder with potentially disabling symptoms ranging from occupational concerns to mental health difficulties. Recent advances related to the neurobiological basis of narcolepsy have led to newer pharmacological treatment options and adjunctive behavioral techniques that support symptom management. This article outlines evidence-based pharmacologic therapies, behavioral techniques, and psychosocial costs related to narcolepsy. Psychosocial factors, although frequently acknowledged, deserve further attention and awareness from researchers and providers. The American Academy of Sleep Medicine's (AASM) Quality Measure Drivers and potential future treatment options are also discussed.

show abstract

“…23,24 Central hypersomnia is characterized by diffi culty performing everyday tasks and diffi culty with marital and other relationships. 5,[10][11][12][13][14][15][16][17][23][24][25][26][27][28] Within the health and wellness domain, central hypersomnia is associated with reduced personal mental and physical health, with adults with central hypersomnia reporting elevated levels of depression, sleepiness, weight gain within proximity of onset of symptoms, higher rates of obesity, and higher risk of injury. 20,21,23 Adults with central hypersomnia also report reduced participation in activities.…”

Section: S C I E N T I F I C I N V E S T I G At I O N Smentioning

confidence: 99%

Psychosocial Characteristics of Children with Central Disorders of Hypersomnolence Versus Matched Healthy Children

Avis

Shen²,

Weaver³

et al. 2015

Journal of Clinical Sleep Medicine

View full text Add to dashboard Cite

Background: Hypersomnia of central origin from narcolepsy or idiopathic hypersomnia (IHS) is characterized by pathological levels of excessive daytime sleepiness (EDS). Central hypersomnia has historically been underdiagnosed and poorly understood, especially with respect to its impact on daytime functioning and quality of life in children. Objective: Describe the psychosocial adjustment of children treated for narcolepsy or IHS on school performance, quality of life, and physical/extracurricular activities. Methods: Using a matched case control design, we compared child self-and parent-reported data from thirtythree 8-to 16-year-olds with an established diagnosis of narcolepsy or IHS, according to ICSD-2 criteria, to that of 33 healthy children matched by age, race/ethnicity, gender, and household income. Assessments evaluated academic performance, quality of life and wellness, sleepiness, and participation in extracurricular activities. Results: Compared to healthy controls, children with central hypersomnia had poorer daytime functioning in multiple domains. Children with hypersomnia missed more days of school and had lower grades than healthy controls. Children with hypersomnia had poorer quality of life by both parent and child report. Children with hypersomnia were signifi cantly sleepier, had higher BMI, and were more likely to report a history of recent injury. Finally, children with hypersomnia engaged in fewer after-school activities than healthy controls. Conclusions: A range of signifi cant psychosocial consequences are reported in children with hypersomnia even after a diagnosis has been made and treatments initiated. Health care professionals should be mindful of the psychosocial problems that may present in children with hypersomnia over the course of treatment. Keywords: children, daytime sleepiness, hypersomnolence, daytime functioning Citation: Avis KT, Shen J, Weaver P, Schwebel DC. Psychosocial characteristics of children with central disorders of hypersomnolence versus matched healthy children.

show abstract

Narcolepsy, idiopathic hypersomnolence and related conditions

Cited by 7 publications

References 21 publications

Excessive Daytime Sleepiness

Excessive Daytime Sleepiness

Current and Future Treatment Options for Narcolepsy: A Review

Psychosocial Characteristics of Children with Central Disorders of Hypersomnolence Versus Matched Healthy Children

Contact Info

Product

Resources

About