Naples Prognostic Score and Prediction of Left Ventricular Ejection Fraction in STEMI Patients

Birdal, Oğuzhan; Pay, Levent; Aksakal, Emrah; Yumurtaş, Ahmet Çağdaş; Çinier, Göksel; Yücel, Enver; Tanboğa, İbrahi̇m Hali̇l; Karagöz, Ali; Oduncu, Vecih

doi:10.1177/00033197231161903

Cited by 11 publications

(10 citation statements)

References 47 publications

(66 reference statements)

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“…NPS, first associated with poor prognosis in cancer patients, provides valuable information regarding prognosis in STEMI patients in more recent studies. 28, 29 Birdal et al 30 showed a relationship between NPS and low ejection fraction in patients with STEMI. Karakoyun et al 31 showed the relationship between NPS and acute kidney injury in patients with STEMI.…”

Section: Discussionmentioning

confidence: 99%

The new score predicts 1-year poor outcome in patients with successful percutaneous coronary intervention: Naples prognostic score

AKGÜMÜŞ,

BALUN

2023

Anatolian Current Medical Journal

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Aims: This study investigated the relationship between Naples prognostic score (NPS) and 1-year poor clinical outcomes in patients presenting with non-ST-segment elevation myocardial infarction (NSTEMI). Methods: The study included 121 patients who had NSTEMI and received successful PCI treatment. The researchers calculated NPS using the neutrophil/lymphocyte ratio, lymphocyte/monocyte ratio, serum albumin level, and total cholesterol. The patients were divided into two groups based on their NPS scores: those with scores of 0.1 and 2 and those with scores of 3 and 4. The study compared the occurrence of major cardiovascular events (MACE) such as 1-year all-cause mortality, 1-year nonfatal recurrent MI, and stroke between the two groups. Results: Patients with high NPS scores were observed to have significantly higher all-cause mortality than those with low NPS scores (23.9% vs. 9.3%, p=0.029). When the MACEs of the patients were compared, significantly higher MACE was observed in the high NPS group (39.1% vs. 18.7%, p=0.013). In multivariate logistic regression analysis, creatinine (OR:4,914, CI 95%: 1.310-18,433, p=0.018) and NPS 3-4 (OR:2.565, CI 95%: 1.093-6.017, p=0.030) were independent predictors of MACE. Conclusion: Composite MACEs of non-fatal recurrent MI, cerebrovascular accident, and all-cause death were higher at one year in patients with high NPS who underwent successful percutaneous intervention. High NPS is an indicator of MACE.

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Section: Discussionmentioning

confidence: 99%

The new score predicts 1-year poor outcome in patients with successful percutaneous coronary intervention: Naples prognostic score

AKGÜMÜŞ,

BALUN

2023

Anatolian Current Medical Journal

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“…Moreover, several data for the prognostic significance of the NPS in cardiovascular diseases such as acute coronary syndrome and heart failure has recently been introduced to the literature 10,18,20 . Beyond the prognostic significance of the NPS, Birdal et al 25 have recently described a relationship between the NPS and the low left ventricular ejection fraction in patients with ST‐elevation myocardial infarction. Moreover, Ozkan et al 19 have compared the NPS with several inflammatory markers in predicting coronary artery severity.…”

Section: Discussionmentioning

confidence: 99%

“…8 diseases such as acute coronary syndrome and heart failure has recently been introduced to the literature. 10,18,20 Beyond the prognostic significance of the NPS, Birdal et al 25 have recently described a relationship between the NPS and the low left ventricular ejection fraction in patients with ST-elevation myocardial infarction.…”

Section: Discussionmentioning

confidence: 99%

Clinical implication of the Naples prognostic score on transcatheter aortic valve replacement in patients with severe aortic stenosis

Demirci,

Aslan,

Güner

et al. 2023

Cathet Cardio Intervent

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BackgroundOne of the hallmarks of frailty in patients with severe aortic stenosis (AS) is malnutrition, for which one of the most up‐to‐date scoring systems is the Naples prognostic score (NPS). This study sought to investigate the predictive role of the NPS in determining mortality in patients undergoing transcatheter aortic valve replacement (TAVR) under long‐term follow‐up.MethodsA total of 430 consecutive patients with symptomatic severe AS who underwent TAVR were included retrospectively. The primary endpoint of the study was the long‐term all‐cause mortality. The study population was divided into two groups according to the NPS value, including Group 1 (NPS 0–2) and Group 2 (NPS 3–4).ResultsThe all‐cause mortality occurred in 250 patients (62.5%) patients during a follow‐up time of 40.6 (22.0–69.4) months. During the follow‐up period, all‐cause mortality was higher in Group 2 compared with Group 1 (87.9% vs. 42.9%, p < 0.001). Older age (p < 0.001), chronic obstructive pulmonary disease (p = 0.015), left ventricular ejection fraction (p = 0.021), and being in Group 2 (high NPS) (hazard ratio: 7.058, 95% confidence interval: 5.174–9.629, p < 0.001) were found to be independent predictors of all‐cause mortality at long‐term follow‐up.ConclusionThe NPS as a malnutrition and inflammation marker in patients with severe aortic stenosis who underwent TAVR provides valuable information for all‐cause mortality under long‐term follow‐up.

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“…[ 18 , 19 ] Lately, several studies have been published on STEMI and NPS. Birdal et al [ 10 ] showed that NPS was reversely associated with discharge LVEF in STEMI patients. Saylik et al [ 13 ] demonstrated that NPS was independently associated with long-term mortality in patients with STEMI undergoing primary percutaneous coronary intervention.…”

Section: Discussionmentioning

confidence: 99%

Naples Prognostic Score and Clinical Outcomes in Pulmonary Arterial Hypertension Patients

Arugaslan

2023

Sisli Etfal

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Objectives Pulmonary arterial hypertension (PAH) is a specific form of pulmonary hypertension characterized by an increased mean pulmonary arterial pressure. Risk stratification is crucial in managing PAH, using various clinical, laboratory, and imaging parameters. The Naples prognostic score (NPS), incorporating nutritional and inflammatory markers, has demonstrated prognostic value in other conditions but not in PAH. The goal of this study was to appraise the importance of NPS as a prognostic indicator for patients with PAH. Methods This retrospective study involved 101 PAH patients. Echocardiographic, laboratory, and right heart catheterization data were collected. Statistical analyses compared variables between survivors and non-survivors, and multivariate logistic regression identified mortality risk factors. Results Among the 101 patients, 18 died within the follow-up period. The mortality group showed elevated levels of B-type natriuretic peptide (BNP) and significantly higher median NPS. Patients were categorized based on their NPS scores, revealing higher mortality in Group 2. Multivariate logistic regression identified age and BNP levels as independent predictors of mortality. The inclusion of NPS in the model further reinforced its association with mortality. Conclusion The study suggests that NPS is linked to poor outcomes in PAH patients. NPS, a straightforward and easily calculated score, holds the potential to predict the clinical trajectory of PAH, offering advantages for risk assessment in this population.

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Naples Prognostic Score and Prediction of Left Ventricular Ejection Fraction in STEMI Patients

Cited by 11 publications

References 47 publications

The new score predicts 1-year poor outcome in patients with successful percutaneous coronary intervention: Naples prognostic score

The new score predicts 1-year poor outcome in patients with successful percutaneous coronary intervention: Naples prognostic score

Clinical implication of the Naples prognostic score on transcatheter aortic valve replacement in patients with severe aortic stenosis

Naples Prognostic Score and Clinical Outcomes in Pulmonary Arterial Hypertension Patients

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