Nanotube platforms for effective drug delivery applications

Adetunji, Charles Oluwaseun; Ogundolie, Frank Abimbola; Mathew, John Tsado; Inobeme, Abel; Titilayo, Olotu; Olaniyan, Olugbemi T.; Ghazanfar, Shakira; Ijabadeniyi, Oluwatosin Ademola; Ajiboye, Modupe Doris; Ajayi, Olulope Olufemi; Dauda, Wadazani; Adetunji, Juliana Bunmi

doi:10.1016/b978-0-323-91376-8.00005-7

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…4−7 Preservation of food at low temperatures is an important technique for extending its shelf life, but it suffers from its rising energy costs along with high carbon emissions. 8,9 Nanoparticle coating is another important form of food preservation, which allows prevention of microorganisms and retains moisture in it to assist its extended shelf life maintaining its quality and freshness. 10,11 In addition to these food preserving methods, pulsed light (PL) techniques have drawn significant attention in recent years due to their efficacy in microbial decontamination without the need for chemical treatments.…”

Section: Introductionmentioning

confidence: 99%

Sustainable Novel Food Coating of Chitosan–Acetylated Gallic Acid Nanoparticles with Pulsed Light Treatment: A Promising Edible Food Preservative

Roy,

Manna,

Gayen

et al. 2024

ACS Food Sci. Technol.

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Herein, the investigation demonstrates the first report on the use of a novel coat of chitosan–acetylated gallic acid nanoparticles (CAG-NPs) along with pulsed light treatment for food preservation with prolonged shelf life, maintaining good nutritional integrity in comparison to chitosan and chitosan–gallic acid nanoparticles or chitosan gallate (CG-NPs). Acetylation was made to overcome the high solubility problem of the CG-NP food coat, which was difficult for commercialization. A number of characterization techniques were used to confirm the structural integrity of CAG-NPs such as nuclear magnetic resonance (NMR), ultraviolet–visible spectroscopy (UV–vis), dynamic light scattering (DLS), powder X-ray diffraction (PXRD), and scanning electron microscopy (SEM). The DPPH assay was performed to determine the remarkable 69% scavenging rate of the synthesized CAG-NPs. Antimicrobial activity was checked, and it was found that CAG-NP was highly efficient against food spoilage pathogens. Subsequently, the synergistic impact of the CAG-NP coat and pulsed light treatment was investigated, referring to papaya as the model food for its preservation. Nutritional analyses were conducted following standard protocols such as the phenol–sulfuric acid, biuret, and standard Soxhlet method followed by a rigorous statistical assessment involving Python3, analysis of variance (ANOVA), and Tukey tests to gauge the significance. Determination of physical and chemical qualities was conducted utilizing established protocols such as weight loss measurement, total soluble solids (TSSs), pH, and ascorbic acid content estimation method for finding the significance of the CAG-NP edible coat over others such as CG-NPs, chitosan along with or without pulsed light treatment. The CAG-NPs show an average diameter of 295 nm, confirmed by the DLS experimental data.

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Section: Introductionmentioning

confidence: 99%

Sustainable Novel Food Coating of Chitosan–Acetylated Gallic Acid Nanoparticles with Pulsed Light Treatment: A Promising Edible Food Preservative

Roy,

Manna,

Gayen

et al. 2024

ACS Food Sci. Technol.

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Properties and Characteristics of Nanocoatings for Medicinal Applications

Mathew,

Inobeme,

Abdullahi

et al. 2024

Sustainable Approach to Protective Nanocoatings

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Nanotechnology has emerged as a revolutionary field with diverse applications, including nanocoatings for medicinal purposes. Nanocoatings, with their unique properties and capabilities, have opened new avenues for drug delivery, medical devices, and antimicrobial treatments. Nanocoatings can be engineered to encapsulate therapeutic agents, protecting them from degradation and facilitating targeted delivery to specific tissues or cells. The use of antimicrobial nanocoatings on medical surfaces has also shown promising results in preventing infections and combating antibiotic-resistant pathogens. While nanocoatings offer tremendous potential, concerns about potential toxicity, biocompatibility, and long-term effects require rigorous evaluation and testing. Furthermore, the study highlights ongoing research and future prospects in the field of medicinal nanocoatings. The development of multifunctional nanocoatings that combine drug delivery, sensing capabilities, and tissue regeneration holds promise for personalized medicine and advanced therapeutics.

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Nanotube platforms for effective drug delivery applications

Cited by 2 publications

References 33 publications

Sustainable Novel Food Coating of Chitosan–Acetylated Gallic Acid Nanoparticles with Pulsed Light Treatment: A Promising Edible Food Preservative

Sustainable Novel Food Coating of Chitosan–Acetylated Gallic Acid Nanoparticles with Pulsed Light Treatment: A Promising Edible Food Preservative

Properties and Characteristics of Nanocoatings for Medicinal Applications

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