Nanotheranostic Carbon Dots as an Emerging Platform for Cancer Therapy

Abstract

Cancer remains one of the most deadly diseases globally, but carbon-based nanomaterials have the potential to revolutionize cancer diagnosis and therapy. Advances in nanotechnology and a better understanding of tumor microenvironments have contributed to novel nanotargeting routes that may bring new hope to cancer patients. Several low-dimensional carbon-based nanomaterials have shown promising preclinical results; as such, low-dimensional carbon dots (CDs) and their derivatives are considered up-and-coming candidates for cancer treatment. The unique properties of carbon-based nanomaterials are high surface area to volume ratio, chemical inertness, biocompatibility, and low cytotoxicity. It makes them well suited for delivering chemotherapeutics in cancer treatment and diagnosis. Recent studies have shown that the CDs are potential applicants in biomedical sciences, both as nanocarriers and nanotransducers. This review covers the most commonly used CD nanoparticles in nanomedicines intended for the early diagnosis and therapy of cancer.

Remote Temperature-Responsive Parafilm Dermal Patch for On-Demand Topical Drug Delivery

“…On day 7, the lidocaine-loaded PP film, neomycin-loaded PP film, standard Band-Aid film, and neomycin-loaded PP film with mild heat group showed thicker and better healing, whereby the wound incision site was observed to be closed. In contrast, the bare PP film and dye-loaded PP film groups demonstrated inferior healing [ 35 , 36 ]. Moreover, compared with the no-heat group, the mild heat treatment group showed better and earlier recovery from the wound.…”

Carbon Dot Nanoparticles: Exploring the Potential Use for Gene Delivery in Ophthalmic Diseases

“…CDs showed strong absorbance in the 280-360 nm UV region with tail extending into visible region where absorption band are assigned to n-π * transition of C=O/C=N bond or π-π * transition of C=C bond [37,38]. The absorption band and emission properties of CDs can be regulated by types and content of surface modifications or surface functional groups, π-conjugated domains or variation of oxygen/nitrogen content in carbon core.…”

Nanoscale Carbon-Polymer Dots for Theranostics and Biomedical Exploration

“…However, the unique polymeric properties of CPDs nanomaterials make them well-suited for the different biomedical fields. Recent studies have shown that CPDs are potential candidates in biomedical sciences, both as nanocarriers and nanotransducers [43][44][45][46]. CPDs are a potential candidate for the researcher to develop novel functional materials.…”