Nanotechnology for blood test to predict the blood diseases/blood disorders

Meenambiga, Setti Sudharsan; Sakthiselvan, Punniavan; Hari, Sowmya; Umai, Devasena

doi:10.1016/b978-0-12-823971-1.00005-2

Cited by 3 publications

(4 citation statements)

References 83 publications

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“…Metal nanowires/nanofibers can be used as building blocks for metal-based PCTs on a smaller scale. Typically, metal nanowires show a very high aspect ratio of 1000 or larger and a low diameter ranging from 10 to 200 nm . The synthesis of metal nanowires usually involves the anisotropic growth of metals on hard or soft templates, through the chemical solution-phase or vapor-phase method .…”

Section: Materials and Methods To Fabricate Pctsmentioning

confidence: 99%

“…Typically, metal nanowires show a very high aspect ratio of 1000 or larger and a low diameter ranging from 10 to 200 nm. 189 The synthesis of metal nanowires usually involves the anisotropic growth of metals on hard or soft templates, through the chemical solution-phase or vapor-phase method. 177 The commonly used hard templates include aluminum oxides, mesoporous oxides, and CNTs.…”

Section: Metalsmentioning

confidence: 99%

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Porous Conductive Textiles for Wearable Electronics

Ding,

Jiang,

et al. 2024

Chem. Rev.

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Over the years, researchers have made significant strides in the development of novel flexible/stretchable and conductive materials, enabling the creation of cutting-edge electronic devices for wearable applications. Among these, porous conductive textiles (PCTs) have emerged as an ideal material platform for wearable electronics, owing to their light weight, flexibility, permeability, and wearing comfort. This Review aims to present a comprehensive overview of the progress and state of the art of utilizing PCTs for the design and fabrication of a wide variety of wearable electronic devices and their integrated wearable systems. To begin with, we elucidate how PCTs revolutionize the form factors of wearable electronics. We then discuss the preparation strategies of PCTs, in terms of the raw materials, fabrication processes, and key properties. Afterward, we provide detailed illustrations of how PCTs are used as basic building blocks to design and fabricate a wide variety of intrinsically flexible or stretchable devices, including sensors, actuators, therapeutic devices, energy-harvesting and storage devices, and displays. We further describe the techniques and strategies for wearable electronic systems either by hybridizing conventional off-the-shelf rigid electronic components with PCTs or by integrating multiple fibrous devices made of PCTs. Subsequently, we highlight some important wearable application scenarios in healthcare, sports and training, converging technologies, and professional specialists. At the end of the Review, we discuss the challenges and perspectives on future research directions and give overall conclusions. As the demand for more personalized and interconnected devices continues to grow, PCT-based wearables hold immense potential to redefine the landscape of wearable technology and reshape the way we live, work, and play.

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Section: Materials and Methods To Fabricate Pctsmentioning

confidence: 99%

Section: Metalsmentioning

confidence: 99%

Porous Conductive Textiles for Wearable Electronics

Ding,

Jiang,

et al. 2024

Chem. Rev.

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“…Ag, Au, graphene, silica, and quantum-based nanostructures have been studied widely to demonstrate their diagnostic and therapeutic properties in various disorders, including hemoglobinopathies [ 47 ]. The potent role of nanoparticles and nanosensors in the diagnosis of anemia, blood cancer, or other bleeding disorders including thalassemia has been under investigation by researchers to develop certain effective, and cost-efficient methods with higher sensitivities [ 67 ].…”

Section: Nanobiosensor For the Diagnosis Of Thalassemiamentioning

confidence: 99%

Thalassemia and Nanotheragnostics: Advanced Approaches for Diagnosis and Treatment

Tariq

Qadeer²,

Anjum

et al. 2023

Biosensors

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Thalassemia is a monogenic autosomal recessive disorder caused by mutations, which lead to abnormal or reduced production of hemoglobin. Ineffective erythropoiesis, hemolysis, hepcidin suppression, and iron overload are common manifestations that vary according to genotypes and dictate, which diagnosis and therapeutic modalities, including transfusion therapy, iron chelation therapy, HbF induction, gene therapy, and editing, are performed. These conventional therapeutic methods have proven to be effective, yet have several disadvantages, specifically iron toxicity, associated with them; therefore, there are demands for advanced therapeutic methods. Nanotechnology-based applications, such as the use of nanoparticles and nanomedicines for theragnostic purposes have emerged that are simple, convenient, and cost-effective methods. The therapeutic potential of various nanoparticles has been explored by developing artificial hemoglobin, nano-based iron chelating agents, and nanocarriers for globin gene editing by CRISPR/Cas9. Au, Ag, carbon, graphene, silicon, porous nanoparticles, dendrimers, hydrogels, quantum dots, etc., have been used in electrochemical biosensors development for diagnosis of thalassemia, quantification of hemoglobin in these patients, and analysis of conventional iron chelating agents. This review summarizes the potential of nanotechnology in the development of various theragnostic approaches to determine thalassemia-causing gene mutations using various nano-based biosensors along with the employment of efficacious nano-based therapeutic procedures, in contrast to conventional therapies.

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“…Silisyum nanotellerle birleştirilen gümüş NP'ler, yüzeyde güçlendirilmiş raman spektroskopisi (SERS) artırma yetenekleri nedeniyle dikkat çekmiştir. DNA'daki mutasyonlar, altın nanopartikül-silikon nanotel kullanılarak tasarlanan moleküler işaret probları kullanılarak tespit edilebilmektedir 62 . Aynı zamanda antikor veya oligonükleotidler ile fonksiyonelleştirilerek tümör biomarker proteinlerinin algılanmasında da kullanılabilirler 54 .…”

Section: Nanotel (Nw)unclassified

Kanser Tedavisi İçin MikroRNA’ların Çok İşlevli Nano-taşıyıcılar İle Dağıtımı

Dağlioğlu

YÜKSEL

2023

Arşiv Kaynak Tarama Dergisi

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Hücre proliferasyonu ve apoptozis gibi kanserden sorumlu biyolojik süreçlerde etkili olan miRNA’lar, farklı kanser türleri ve evrelerinin teşhis ve tedavisinde yeni biyobelirteçler olarak işlev görür. Bunun yanı sıra bazı miRNA’ların onkogen ve tümör baskılayıcı özelliği nanoteknoloji ile entegre edilmesiyle kanser oluşumunu engeller. Son yıllarda miRNA’ların kanser tedavisinde kullanılmasını sağlayan diğer bir yaklaşım ise nano-taşıyıcılardır. İlaçlar, peptitler veya genler gibi aktif bileşikleri taşımak için geliştirilen bu nano-taşıyıcıların kanser tedavisinde kullanımları umut vadetmektedir. Bu derleme, miRNA dağıtımında kullanılan nano-taşıyıcı türleri hakkında kısa bir bilgi sunmaktadır. Ayrıca nanoteknolojideki gelişmelerle birlikte miRNA’ların kanser teşhis ve tedavisinde kullanımın yanısıra gen susturma mekanizması olan RNA interferansından kısaca bahsedilmektedir.

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Nanotechnology for blood test to predict the blood diseases/blood disorders

Cited by 3 publications

References 83 publications

Porous Conductive Textiles for Wearable Electronics

Porous Conductive Textiles for Wearable Electronics

Thalassemia and Nanotheragnostics: Advanced Approaches for Diagnosis and Treatment

Kanser Tedavisi İçin MikroRNA’ların Çok İşlevli Nano-taşıyıcılar İle Dağıtımı

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