Nanotechnology enabled regenerative medicine for neurological disorders

Lowe, Timothy J.; Agrahari, Vivek; Kannan, Rangaramanujam M.; Kannan, Sujatha

doi:10.1016/j.addr.2019.11.006

Cited by 7 publications

(2 citation statements)

References 14 publications

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“…Such therapies target the correction or the optimization of an impaired regeneration resulting from a disease, a physiological adaptation or even therapeutic side effects. Regenerative medicine research involve multiple areas from stem cells [31], gene editing [37], nuclear transfer [38], proteomics, pharmacology, nanotechnology [39], tissue, engineering and three-dimensional printing [40]. Beside the various adjuvant used in regenerative medicine, mainly pharmacological (regenerative pharmacology) [41][42][43] or bioengineering [28,44], we aim to highlight the importance of lifestyle and how it impacts regeneration.…”

Section: Regeneration and Medicinementioning

confidence: 99%

Exercise, Diet and Sleeping as Regenerative Medicine Adjuvants: Obesity and Ageing as Illustrations

2022

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Regenerative medicine uses the biological and medical knowledge on how the cells and tissue regenerate and evolve in order to develop novel therapies. Health conditions such as ageing, obesity and cancer lead to an impaired regeneration ability. Exercise, diet choices and sleeping pattern have significant impacts on regeneration biology via diverse pathways including reducing the inflammatory and oxidative components. Thus, exercise, diet and sleeping management can be optimized towards therapeutic applications in regenerative medicine. It could allow to prevent degeneration, optimize the biological regeneration and also provide adjuvants for regenerative medicine.

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Section: Regeneration and Medicinementioning

confidence: 99%

Exercise, Diet and Sleeping as Regenerative Medicine Adjuvants: Obesity and Ageing as Illustrations

2022

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“…Thus, increasing research interest has been noticed in designing advanced repair strategies for spinal cord regeneration. Particular attention has been drawn to biomaterials and nanotechnologyenabled products for the controlled delivery and sustained release of various moieties, including drugs, bioactive molecules, imaging agents, and cells [12][13][14][15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Novel Strategies for Spinal Cord Regeneration

Costăchescu

Niculescu

Dabija

et al. 2022

IJMS

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A spinal cord injury (SCI) is one of the most devastating lesions, as it can damage the continuity and conductivity of the central nervous system, resulting in complex pathophysiology. Encouraged by the advances in nanotechnology, stem cell biology, and materials science, researchers have proposed various interdisciplinary approaches for spinal cord regeneration. In this respect, the present review aims to explore the most recent developments in SCI treatment and spinal cord repair. Specifically, it briefly describes the characteristics of SCIs, followed by an extensive discussion on newly developed nanocarriers (e.g., metal-based, polymer-based, liposomes) for spinal cord delivery, relevant biomolecules (e.g., growth factors, exosomes) for SCI treatment, innovative cell therapies, and novel natural and synthetic biomaterial scaffolds for spinal cord regeneration.

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Nanotherapeutics for Neurological Disorders

Ravindranath,

Grewall

2023

Theranostic Applications of Nanotechnology in Neurological Disorders

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Nanotechnology enabled regenerative medicine for neurological disorders

Cited by 7 publications

References 14 publications

Exercise, Diet and Sleeping as Regenerative Medicine Adjuvants: Obesity and Ageing as Illustrations

Exercise, Diet and Sleeping as Regenerative Medicine Adjuvants: Obesity and Ageing as Illustrations

Novel Strategies for Spinal Cord Regeneration

Nanotherapeutics for Neurological Disorders

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