Nanotechnology developments: opportunities for animal health and production

Manuja, Anju; Kumar, Balvinder; Singh, Raj Kumar

doi:10.4081/nd.2012.e4

Cited by 56 publications

(45 citation statements)

References 76 publications

(54 reference statements)

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“…The nanoformulations have been successfully used for drug delivery against bacterial, fungal and protozoan diseases including Trypanosoma cruzi in animal models of disease [20]. However, there are no reports of polymerbased nanoformulations against T. evansi.…”

Section: Discussionmentioning

confidence: 99%

Quinapyramine Sulfate-Loaded Sodium Alginate Nanoparticles Show Enhanced Trypanocidal Activity

et al. 2014

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Section: Discussionmentioning

confidence: 99%

Quinapyramine Sulfate-Loaded Sodium Alginate Nanoparticles Show Enhanced Trypanocidal Activity

et al. 2014

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“…Algumas nanoformulações têm sido empregadas de forma bem-sucedida para a entrega de fármacos no combate de fungos, protozoários e doenças bacterianas como a candidíase, leishmaniose, salmonelose, brucelose e tuberculose em testes com animais, 7 demonstrando o grande potencial do uso de nanocarreadores como sistemas de entrega de fármacos e vacinas para o combate de doenças em animais.…”

Section: Introductionunclassified

Sistemas carreadores lipídicos nanoestruturados para ivermectina e metopreno visando controle de parasitas

Cola¹,

Pasquoto²,

Guilger³

et al. 2016

Quim. Nova

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CONTROL. The study of characteristics of nanoscale structures and applications now has great interest of researchers from different areas. In this regard, lipid carriers can improve the bioavailability of drugs and the reduction of possible toxicological effects. Thus, the development of nanostructured systems for the agricultural sector, aimed at combating parasites may reduce extensive damage caused to livestock producers and animal health. This study aimed to prepare and characterize lipid carrier systems, such as Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC), as well as evaluate the potential of cyto and genotoxicity of these systems in order to improve and produce alternatives to the use targeting these compounds in veterinary applications. Lipid nanoparticles had become spherical with an average size of 250 nm and remained stable over 120 days. The encapsulation efficiency was greater than 99% for both drugs and release tests showed a strong interaction between drugs and nanoparticles. Cyto-and genotoxicity tests show that nanoparticles made possible changes in cellular viability of the tested cells. Thus, the results showed that the nanoparticles had good colloidal characteristics without changes in its characteristics, enabling the development of carrier systems for these drugs , aiming veterinary applications.Keywords: lipid nanocarriers; parasites; veterinary; genotoxicity; cytotoxicity. INTRODUÇÃOO estudo de características e aplicações de estruturas em escala nanométrica tem apresentado um grande interesse a pesquisadores das áreas médica (humana e animal), ambiental e agrícola. Estas estruturas nanométricas, preparadas de diferentes formas, permitiram o avanço da nanotecnologia. Dentre essas estruturas, destacam-se os nanocarreadores, que permitem melhorar a biodisponibilidade de muitos compostos bioativos, como, por exemplo, o aumento da solubilidade aquosa, melhorando assim processos de absorção e distribuição tecidual (farmacocinética) e também a diminuição de possíveis efeitos tóxicos (redução da toxidade local e sistêmica).1 O desenvolvimento da nanotecnologia permitirá seu uso na produção animal em forma de monitoramento ou mesmo de aplicação direta de produtos nanotecnológicos na saúde, na alimentação, controle de parasitas, conforto térmico e ambiental desses animais. 2A nanotecnologia apresenta grande potencial para as pesquisas, possibilitando o desenvolvimento de novos produtos destinados à melhoria da sanidade e saúde animal, o que propicia produtos derivados de animais com maior qualidade e segurança, além de possibilitar potenciais aplicações na área da medicina veterinária, que incluem sistemas de diagnóstico e tratamento de doenças, novas ferramentas para o melhoramento molecular e celular, modificação de resíduos animais, detecção de patógenos, isolamento de toxinas, vetores para o transporte de fármacos, 3 entre outros. Os avanços da nanotecnologia trazem possíveis consequências econômicas, sociais, ambientais e políticas.4-6 A aplicação de nanotecnologia ...

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“…To treat these affections the therapeutic agents have to penetrate inside cells and able to cross the blood brain barrier. This is not possible with existing macro molecular therapeutic substances, but the nanoparticles can act against intracellular pathogens and brain tumors due to their small size [8]. This review deals with the potential applications of ZnO NPs in veterinary sciences.…”

Section: Introductionmentioning

confidence: 99%

Zinc Oxide Nanoparticles: Opportunities and Challenges in Veterinary Sciences

Manuja¹

2015

Immunome Res

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Nanotechnology has opened up new vistas for applications in almost all the disciplines of veterinary and animal sciences. Zinc oxide (ZnO) has been used as an alternative to antibiotics in animal feed. It has also been widely used for wound healing and various skin disorders. Recently ZnO nanoparticles (NPs) have attracted attention owing to their unique features. There can be numerous applications of ZnO NPs due to their antibacterial, antineoplastic, wound healing, ultraviolet scattering and angiogenic properties. These have also been used to promote tissue repair, as a food preservative and as feed additive. This paper reviews the recent developments in ZnO NPs research and its potential for application in animal health and production.

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Nanotechnology developments: opportunities for animal health and production

Cited by 56 publications

References 76 publications

Quinapyramine Sulfate-Loaded Sodium Alginate Nanoparticles Show Enhanced Trypanocidal Activity

Quinapyramine Sulfate-Loaded Sodium Alginate Nanoparticles Show Enhanced Trypanocidal Activity

Sistemas carreadores lipídicos nanoestruturados para ivermectina e metopreno visando controle de parasitas

Zinc Oxide Nanoparticles: Opportunities and Challenges in Veterinary Sciences

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