Nanotechnology-based Approaches for Efficient Wound Monitoring and Healing

Abstract

Wound healing is a complex physiological process consisting of several biological and immunological mechanisms which are mutually inclusive. Wounds are commonly categorized as acute and chronic wounds. Acute wound healing is dynamic and chronic wound healing proceeds in a prolonged and irregular manner; thus, it calls for proper management. Certain problems associated to wound healing have triggered the researchers to come up with a promising approach and so nanotechnology-based approaches have evolved as a driving force in wound healing. Nanotechnology has led to the fabrication of nanoparticles, biomolecule loaded dressings and smart dressings to accelerate the wound healing. Nanobiosensors are also being developed which can monitor wound conditions with great precision and incredible sensitivity. This review concentrates on novel nanoscale approaches for instance, nanoparticles such as gold, silver, polystyrene, chitosan, zinc peroxide and nanomaterials such as nano-sensors, nanoflares, nanofibers, etc. for effective wound monitoring and healing. The efficacy of nanomaterial based therapeutic agents in wound healing has been expressed herein. The significance of nanoscale systems in wound healing in terms of anti-microbial activity, angiogenesis, drug delivery, collagen deposition and stem cell delivery has also been addressed.