2015
DOI: 10.1016/j.ijantimicag.2015.01.016
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Nanotechnology approaches for antibacterial drug delivery: Preparation and microbiological evaluation of fusogenic liposomes carrying fusidic acid

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Cited by 48 publications
(34 citation statements)
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References 24 publications
(35 reference statements)
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“…12 It is therefore prepared as the diethanolamine salt for intravenous administration and as sodium salt for oral administration. 22 Different nanocarrier systems such as microemulsion, 23 liposomes, 24,25 polymeric micropheres 26 and polymeric nanobers 27 were reported for the delivery of FSD alone or in combination with other antibiotics. However, all these formulations need tedious preparation procedures and use of organic solvents.…”
Section: Introductionmentioning
confidence: 99%
“…12 It is therefore prepared as the diethanolamine salt for intravenous administration and as sodium salt for oral administration. 22 Different nanocarrier systems such as microemulsion, 23 liposomes, 24,25 polymeric micropheres 26 and polymeric nanobers 27 were reported for the delivery of FSD alone or in combination with other antibiotics. However, all these formulations need tedious preparation procedures and use of organic solvents.…”
Section: Introductionmentioning
confidence: 99%
“…To overcome the disadvantages of traditional eye drops, several ocular drug delivery systems have been developed in recent years, such as in-situ gels [4], microemulsions [5], microspheres [6], liposomes [7], solid lipid nanoparticles (SLN) [8], and nanostructured lipid carriers (NLC) [9]. Among them, liposomes have a great potential for penetration enhancement and high biocompatibility [10,11] .…”
Section: Introductionmentioning
confidence: 99%
“…In the field of ophthalmology, liposome become the ideal drug delivery systems because its structure is like cell membrane and it has good biocompatibility, what's more, it can wrap both hydrophilic and hydrophobic drugs. Nicolosi et al (2015) prepared the fusidic acid coated by liposome to improve its antibacterial effect and its ability of penetrating cells. The results showed that the antibacterial ability of fusidic acid has been improved dramatically when it was coated by liposome, at the same time, the effective drug concentration and the dose decreased.…”
Section: Liposomesmentioning
confidence: 99%