Nanotechnology Applied to Cellulosic Materials

Fernandes, Ana Patrícia; Cruz‐Lopes, Luísa; Esteves, Bruno; Evtuguin, Dmitry V.

doi:10.3390/ma16083104

Cited by 11 publications

(4 citation statements)

References 119 publications

(335 reference statements)

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“…These production methods with advantages and disadvantages can be presented in Figure 3. Microbial sources for producing nanofibers are considered an important approach, which is applied to many fields such as bacterial cellulose nanofiber [38], microbial fuel cells [39], microbial polysaccharides for controlled drug release [40], and monitoring of food packaging [41]. These fields will be discussed in the following sections.…”

Section: Nanofibers In Water Energy and Foodmentioning

confidence: 99%

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Biotechnology of Nanofiber in Water, Energy, and Food Sectors

Prokisch,

Sári,

Muthu

et al. 2023

Agronomy

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Natural resources including water, energy, and food have an increase in demand due to the global population increases. The sustainable management of these resources is an urgent global issue. These resources combined in a very vital nexus are called the water–energy–food (WEF) nexus. The field of nanotechnology offers promising solutions to overcome several problems in the WEF nexus. This review is the first report that focuses on the suggested applications of nanofibers in the WEF sectors. An economic value of nanofibers in WEF sectors was confirmed, which was mainly successfully applied for producing clean water, sustainable energy, and safe food. Biotechnological solutions of nanofibers include various activities in water, energy, and food industries. These activities may include the production of fresh water and wastewater treatment, producing, converting, and storing energy, and different activities in the food sector. Furthermore, microbial applications of nanofibers in the biomedicine sector, and the most important biotechnological approaches, mainly plant tissue culture, are the specific focus of the current study. Applying nanofibers in the field of plant tissue culture is a promising approach because these nanofibers can prevent any microbial contamination under in vitro conditions, but the loss of media by evaporation is the main challenge in this application. The main challenges of nanofiber production and application depend on the type of nanofibers and their application. Different sectors are related to almost all activities in our life; however, enormous open questions still need to be answered, especially the green approach that can be used to solve the accumulative problems in those sectors. The need for research on integrated systems is also urgent in the nexus of WEF under the umbrella of environmental sustainability, global climate change, and the concept of one’s health.

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Section: Nanofibers In Water Energy and Foodmentioning

confidence: 99%

“…Agronomy 2023, 13, x FOR PEER REVIEW 3 of 33 nanofiber [38], microbial fuel cells [39], microbial polysaccharides for controlled drug release [40], and monitoring of food packaging [41]. These fields will be discussed in the following sections.…”

Section: Nanofibers In Water Energy and Foodmentioning

confidence: 99%

Biotechnology of Nanofiber in Water, Energy, and Food Sectors

Prokisch,

Sári,

Muthu

et al. 2023

Agronomy

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“…This is a promising route, as conventional routes require complex catalysts and sometimes require high temperatures (Table 16). Several examples of ultrasound-assisted oxidation and hydrolysis reactions to produce nanocrystals from lignocellulosic biomass were recently reviewed [124].…”

Section: Examples Of Oxidationsmentioning

confidence: 99%

Microwaves and Ultrasound as Emerging Techniques for Lignocellulosic Materials

Fernandes,

Cruz-Lopes,

Esteves

et al. 2023

Materials

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Currently, in the context of biorefinery and bioeconomy, lignocellulosic biomass is increasingly used to produce biofuels, biochemicals and other value-added products. Microwaves and ultrasound are emerging techniques that enable efficient and environmentally sustainable routes in the transformation of lignocellulosic biomass. This review presents some of the most important works published in the last few years on the application of microwaves and/or ultrasound in lignocellulosic materials pretreatment and can be used as a starting point for research into this theme. This review is divided into four parts. In Part I, the theoretical fundamentals of microwave and ultrasound treatments are reviewed. Dielectric constants for biomass, factors that influence pretreatment, are some of the subjects addressed. In Part II, the effects that these techniques have on lignocellulosic biomass (on the size and surface area of the particle; on the content of lignin, hemicellulose and cellulose; on the crystallinity index of cellulose; on the effect of solubilization of organic matter; on hydrolysis and reduction of sugars) are discussed. In Part III, emphasis is given to the contribution of microwaves and ultrasound in obtaining value-added products. In this context, several examples of liquefaction and extraction procedures are presented. Part IV describes examples of performing sonocatalysis on lignocellulosic biomass to obtain value-added products, such as furfural, whose production is significantly reduced by ultrasound treatment.

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“…Non-spherical NPs are generally fabricated using particle replication [ 17 ], microfluidics [ 18 ], film stretching, self-assembly [ 19 ], laser ablation [ 20 ], and high-pressure homogenization [ 21 , 22 ]. So far, non-spherical NPs, such as rod, tube, square, octahedron, star [ 23 ], cube, bowl [ 24 ], filament [ 25 ], cluster, disc, flower, needle, star, and spindle, which consist of polymer, carbon, silica, or metal, have been fabricated and reported [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Biocompatible Snowman-like Dimer Nanoparticles for Improved Cellular Uptake in Intrahepatic Cholangiocarcinoma

Chen

Liu

et al. 2023

Pharmaceutics

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Intrahepatic cholangiocarcinoma (ICC) is one of the most aggressive types of human cancers. Although paclitaxel (PTX) was proven to exert potent anti-tumor effects against ICC, the delivery of PTX is still challenging due to its hydrophobic property. Nanoparticle (NP)-based carriers have been proven to be effective drug delivery vehicles. Among their physicochemical properties, the shape of NPs plays a crucial role in their performance of cellular internalization and thus anti-tumor efficacy of loaded drugs. In this study, dumbbell-like and snowman-like dimer NPs, composed of a polylactic acid (PLA) bulb and a shellac bulb, were designed and prepared as drug nanocarriers to enhance the efficiency of cellular uptake and anti-tumor performance. PLA/shellac dimer NPs prepared through rapid solvent exchange and controlled co-precipitation are biocompatible and their shape could flexibly be tuned by adjusting the concentration ratio of shellac to PLA. Drug-loaded snowman-like PLA/shellac dimer NPs with a sharp shape exhibit the highest cellular uptake and best cell-killing ability against cancer cells in an in vitro ICC model over traditional spherical NPs and dumbbell-like dimer NPs, as proven with the measurements of flow cytometry, fluorescent confocal microscopy, and the CCK8 assay. The underlying mechanism may be attributed to the lower surface energy required for the smaller bulbs of snowman-like PLA/shellac dimer NPs to make the initial contact with the cell membrane, which facilitates the subsequent penetration through the cellular membrane. Therefore, these dimer NPs provide a versatile platform to tune the shape of NPs and develop innovative drug nanocarriers that hold great promise to enhance cellular uptake and therapeutic efficacy.

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Nanotechnology Applied to Cellulosic Materials

Cited by 11 publications

References 119 publications

Biotechnology of Nanofiber in Water, Energy, and Food Sectors

Biotechnology of Nanofiber in Water, Energy, and Food Sectors

Microwaves and Ultrasound as Emerging Techniques for Lignocellulosic Materials

Biocompatible Snowman-like Dimer Nanoparticles for Improved Cellular Uptake in Intrahepatic Cholangiocarcinoma

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