Nanotechnology: A novel tool to enhance the bioavailability of micronutrients

Arshad, Rizwan; Gulshad, Lubaba; Haq, Iahtisham‐Ul; Farooq, Muhammad Adil; Al‐Farga, Ammar; Siddique, Rabia; Manzoor, Muhammad Faisal; Karrar, Emad

doi:10.1002/fsn3.2311

Cited by 56 publications

(31 citation statements)

References 51 publications

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“…Various nano-based delivery systems have been investigated to improve the bioavailability of encapsulated pharmaceuticals and nutraceuticals, as illustrated in Figure 1 [ 25 , 26 ]. Nanotechnology has been recognized for its promising and superior delivery of natural products for chemoprevention and chemotherapy compared to traditional formulations [ 2 ].…”

Section: Resultsmentioning

confidence: 99%

“…Furthermore, the encapsulated formulations improved survival rates and liver and renal safety assessments [33]. [25,26]. Nanotechnology has been recognized for its promising and superior delivery of natural products for chemoprevention and chemotherapy compared to traditional formulations [2].…”

Section: Nanotechnologymentioning

confidence: 99%

“… Nano-based delivery systems used to improve the bioavailability of encapsulated pharmaceuticals and nutraceuticals [ 25 , 26 ]. …”

Section: Figurementioning

confidence: 99%

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A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability

2021

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Resveratrol (RES) has a low bioavailability. This limitation was addressed in an earlier review and several recommendations were offered. A literature search was conducted in order to determine the extent of the research that was conducted in line with these recommendations, along with new developments in this field. Most of the identified studies were pre-clinical and confirmed the heightened activity of RES analogues compared to their parent compound. Although this has provided additional scientific kudos for these compounds and has strengthened their potential to be developed into phytopharmaceutical products, clinical trials designed to confirm this increased activity remain lacking and are warranted.

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Section: Resultsmentioning

confidence: 99%

Section: Nanotechnologymentioning

confidence: 99%

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A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability

2021

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“…В нектарах содержатся пищевые волокна, которые помогают перистальтике кишечника и способствуют выведению токсинов из организма. Проблема сохранения и поддержания здоровья человека алиментарным путем в последнее время приобретает особую значимость и актуальность благодаря современным достижениям нутрициологии, химии и экологии пищи [8][9][10][11][12][13][14][15][16]. В нектарах присутствуют различные витамины, хоть и в меньших концентрациях, чем в соках.…”

Section: Introductionunclassified

Effect of Water Contamination on the Preservation of Vitamins in Juices

Yustratov

Timoshchuk

Gorelkina

et al. 2021

Food Processing: Techniques and Technology

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Introduction. Whey drinks, fruit nectars, and reconstituted juices are usually based on domestic water. This water may contain various contaminants, which can interact with vitamins in fruit drinks. The research objective was to study the impact of trichloromethane, hydroxybenzene, chlorophenol, trichloroethylene, and ethylene chloride on the state of vitamins in juice products. Study objects and methods. The study featured aqueous fruit and berry concentrates, used in fruit nectar production. The control sample contained water without contaminants, while the test samples involved trichloromethane, trichloroethylene, ethylene chloride, hydroxybenzene, and chlorophenol. Capillary zone electrophoresis made it possible to determine bioactive substances (vitamins) in aqueous fruit and berry concentrates. Molecular absorption spectroscopy in visible spectrum was used to check the color intensity. Gas chromatography helped to analyze the content of contaminants. Results and discussion. The experiment tested vitamin preservation in fruit nectars based on water contaminated with trichloromethane, trichloroethylene, ethylene chloride, hydroxybenzene, and chlorophenol. Trichloromethane did not react with bioactive substances. Trichloroethylene, ethylene chloride, hydroxybenzene, and chlorophenol lowered the content of ascorbic acid, carotene, thiamine, riboflavin, choline, and pyridoxine. Depending on the organic matter, water contamination led to a decrease in carotene by 7–35%, vitamin B1 – by 10–100%, B2 – by 11–100%, B4 – by 8–45%, and B6 – by 8–100 in the finished product. The paper introduces a theoretic substantiation of the interaction between the contaminants and the bioactive substances. Conclusion. Water, contaminated with such organic substances as hydroxybenzene, chlorophenol, trichloroethylene, and ethylene chloride, proved to affect the vitamin preservation in juices, which was illustrated by chemical equations. Therefore, juice production requires preliminary water purification because toxic and cancerogenic substances can decrease the quality and food safety of the finished product.

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“…De hecho, en los últimos años, se ha demostrado que la reducción del tamaño ingredientes o sustancias bioactivas puede ser clave para mejorar la biodisponibilidad de nutrientes, además de reducir la dosificación de ingredientes con efectos negativos para la salud sin que se modifique la palatabilidad del alimento. A su vez, también puede utilizarse para encapsular y liberar de manera controlada una determinada molécula bioactiva en alguna parte del sistema gastrointestinal 1 . Uno de los ejemplos sobre la aplicación de la nanotecnología es la fortificación de la dieta con hierro.…”

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