Nanotechnological interventions in bacteriocin formulations – advances, and scope for challenging food spoilage bacteria and drug-resistant foodborne pathogens

Mohanty, Debapriya; Suar, Mrutyunjay; Panda, Sandeep Kumar

doi:10.1080/10408398.2023.2289184

Cited by 3 publications

(1 citation statement)

References 106 publications

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“…Moreover, in recent years, with the development of nanotechnology and biomaterials science, the application of bacteriocins in novel drug delivery systems and biosensors has also attracted increasing attention [ 54 ]. Taking advantage of its antimicrobial and biocompatibility characteristics, scientists have tried to use bacteriocin to construct antimicrobial coatings, drug sustained release carriers and biosensing elements, further broadening its application range in medical and biotechnology fields.…”

Section: Potential Applications Of Class Iia Bacteriocinsmentioning

confidence: 99%

The Progress of the Biotechnological Production of Class IIa Bacteriocins in Various Cell Factories and Its Future Challenges

Wang,

Shang,

Huang

et al. 2024

IJMS

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Class IIa bacteriocins produced in lactic acid bacteria are short cationic peptides with antimicrobial activity. In the search for new biopreservation agents, class IIa bacteriocins are considered to be the best potential candidates, not only due to their large abundance but also because of their high biological activity and excellent thermal stability. However, regulated by the biosynthetic regulatory system, the natural class IIa bacteriocin yield is low, and the extraction process is complicated. The biotechnological production of class IIa bacteriocins in various cell factories has been attempted to improve this situation. In this review, we focus on the application of biotechnological routes for class IIa bacteriocin production. The drawbacks and improvements in the production of class IIa bacteriocins in various cell factories are discussed. Furthermore, we present the main challenge of class IIa bacteriocins, focusing on increasing their production by constructing suitable cell factories. Recombinant bacteriocins have made considerable progress from inclusion body formation, dissolved form and low antibacterial activity to yield recovery. The development of prospective cell factories for the biotechnological production of bacteriocins is still required, which may facilitate the application of bacteriocins in the food industry.

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Section: Potential Applications Of Class Iia Bacteriocinsmentioning

confidence: 99%

The Progress of the Biotechnological Production of Class IIa Bacteriocins in Various Cell Factories and Its Future Challenges

Wang,

Shang,

Huang

et al. 2024

IJMS

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Natural preservatives used in foods: a review

Cedillo-Olivos,

Juárez-Chairez,

Cid-Gallegos

et al. 2024

Critical Reviews in Food Science and Nutrition

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Instantaneous preparation of gold-carbon dot nanocomposites for on-site SERS identification of pathogens in diverse interfaces

Guo,

Liu,

Luo

et al. 2024

Photon. Res.

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Rapid detection of pathogens present on contaminated surfaces is crucial for food safety and public health due to the high morbidity and mortality of bacterial infections. Herein, a sensitive and efficient method for on-site identification of foodborne pathogens on anisotropic surfaces was developed by using an in situ instantaneously prepared surface-enhanced Raman scattering (SERS) platform. To achieve this, molybdenum-doped gallic acid-derived carbon dots (MCDs) are utilized as the reductant for synthesizing Au@MCDs nanohybrids within just 3 s at ambient temperature. The synergistic effect of the electromagnetic enhancement and charge transfer of Au@MCDs enables excellent SERS performance 10 times stronger than bare Au NPs. The bioassay platform requires less than 5 min to complete the quantitative detection of foodborne pathogens on various microbial-contaminated interfaces with a sensitivity of 10 CFU/mL. This innovative strategy breaks the long-standing limitations of SERS substrates in practical use, such as the time-consuming process, interference of residual surfactants, poor surface stability, and few application scenarios, providing a promising tool for widespread applications in biomedical research and clinical diagnostics.

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Nanotechnological interventions in bacteriocin formulations – advances, and scope for challenging food spoilage bacteria and drug-resistant foodborne pathogens

Cited by 3 publications

References 106 publications

The Progress of the Biotechnological Production of Class IIa Bacteriocins in Various Cell Factories and Its Future Challenges

The Progress of the Biotechnological Production of Class IIa Bacteriocins in Various Cell Factories and Its Future Challenges

Natural preservatives used in foods: a review

Instantaneous preparation of gold-carbon dot nanocomposites for on-site SERS identification of pathogens in diverse interfaces

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