Nanosystems: the use of nanoalloys, metallic, bimetallic, and magnetic nanoparticles in biomedical applications

Abstract

There is a growing interest in the use of nanosystems such as nanoalloys, bimetallic nanoparticles, metallic nanoparticles and magnetic nanoparticles in biomedical applications. These applications can be as diverse as hyperthermic treatments; targeted drug delivery; bio-imaging; cell labelling and gene delivery. The use of nanoalloys in these applications has received only limited attention due to the fact that there were many unanswered questions and concerns regarding nanoparticles and nanoalloys such as their stability over time, tendency to agglomerate, chemical activity, ease of oxidation, biocompatibility and cytotoxicity. In this chapter we survey current applications and advances in magnetic nanoparticles used in these biomedical applications so as to understand the materials properties that can pave the way for the use of nanoalloys as a potential alternative or improve solutions that are offered by current materials.

Laser‐Assisted Synthesis of Colloidal FeWxOy and Fe/FexOy Nanoparticles in Water and Ethanol

“…Most of the available T 1 (spin‐lattice relaxation time) CAs are paramagnetic compounds and those categorized as T 2 (spin‐spin relaxation time) CAs are superparamagnetic iron oxides NPs . Bimetallic nanoparticles (BNPs) attracted attention in medical and technological applications ,. In all cases, Fe oxide was one of the components such as Fe−Co, Fe−Bi, Fe−Ni, Fe−Pt, and the ferrites MnFe 2 O 4 and CoFe 2 O 4 .…”

Live-cell imaging to compare the transfection and gene silencing efficiency of calcium phosphate nanoparticles and a liposomal transfection agent

“…Among the nanosystems, dendrimers, liposomes, polymeric and inorganic nanoparticles have been established. 3, 5, 6, 7, 11, 14, 15, 16, 17 Typical nanoparticles for transfection comprise gold, 18, 19, 20 iron oxide, 21 silica, 22 carbon nanotubes 23 and many different polymers. 2, 24, 25 …”

Investigation of role of urea in morphologically controlled synthesis of calcium‐bismuth bimetallic nanoparticles from chicken egg shells and its catalytic and fuel additive applications

“…Alham et al have synthesized bimetallic nanoalloys of gold, silver, platinum, palladium, copper, and nickel . Nanoalloys are used in therapeutics, bioimaging, electrocatalysis, and drug delivery . Bimetallic alloy nanoparticles are synthesized by solvothermal reactions, microwave irradiation, polyol, chemical etching, microemulsion, and colloidal self‐assembly .…”