Nanostructuring of polymethylpentene by plasma and heat treatment for improved biocompatibility

Slepička, Petr; Trostová, Simona; Kasálková, Nikola Slepičková; Kolská, Zdeňka; Malínský, P.; Macková, Anna; Bačáková, Lucie; Švorčı́k, Václav

doi:10.1016/j.polymdegradstab.2012.04.013

Cited by 48 publications

(21 citation statements)

References 27 publications

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“…Also the different type of cell shape on the basis of plasma exposure was determined. The cells on pristine PMP exhibited rounded shape, were not spread and lacked typical actin protrusions (Figure 5) [81]. Viability of the adhered cells is strongly influenced by the hydrophilicity, chemical changes and surface roughness of the substrate.…”

Section: Plasma Treatmentmentioning

confidence: 99%

Surface Modification of Polymer Substrates for Biomedical Applications

2017

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While polymers are widely utilized materials in the biomedical industry, they are rarely used in an unmodified state. Some kind of a surface treatment is often necessary to achieve properties suitable for specific applications. There are multiple methods of surface treatment, each with their own pros and cons, such as plasma and laser treatment, UV lamp modification, etching, grafting, metallization, ion sputtering and others. An appropriate treatment can change the physico-chemical properties of the surface of a polymer in a way that makes it attractive for a variety of biological compounds, or, on the contrary, makes the polymer exhibit antibacterial or cytotoxic properties, thus making the polymer usable in a variety of biomedical applications. This review examines four popular methods of polymer surface modification: laser treatment, ion implantation, plasma treatment and nanoparticle grafting. Surface treatment-induced changes of the physico-chemical properties, morphology, chemical composition and biocompatibility of a variety of polymer substrates are studied. Relevant biological methods are used to determine the influence of various surface treatments and grafting processes on the biocompatibility of the new surfaces—mammalian cell adhesion and proliferation is studied as well as other potential applications of the surface-treated polymer substrates in the biomedical industry.

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Section: Plasma Treatmentmentioning

confidence: 99%

Surface Modification of Polymer Substrates for Biomedical Applications

2017

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“…Plasma treatment was also used for immobilization of different types of different biopolymers, such as chitosan on low-density polyethylene for bio-medical applications [28]. DC plasma was also successfully used for biocompatibility enhancement of polymethylpentene [29], PLLA [30] or PHB [31].…”

Section: Introductionmentioning

confidence: 99%

“…The increase in contact angle depended on power and treatment time, the highest values observed for FEP during aging were achieved for combination of the highest power and treatment time, i.e. 8 W and 240 s. Some interesting conclusions can be inferred from comparing FEP with polyolefin foils or biodegradable polymers, such as PLLA and PMP[22,29]. The increase in contact angle is not that sharp as for PLLA and PMP, which can be contributed probably to the fact that the surface oxygen containing groups which are present on the very surface of the FEP surface are still surrounded with…”

mentioning

confidence: 96%

“…The fluorine concentration on the very top surface of plasma treated FEP is the main reason of higher hydrophobicity of the surface measured directly after the plasma treatment. These values are much higher both in comparison to plasma treated polyolefine foils[20][21][22][29][30][31] and even more to non-woven substrate, where there were determined almost extremely low values of contact angles[32]. Plasma treatment led to cleavage of macromolecular chains, creation of free radicals and conjugated double bonds[33].…”

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confidence: 99%

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Plasma activated perfluoroethylenepropylene for cytocompatibility enhancement

Slepička

Peterková

Rimpelová

et al. 2016

Polymer Degradation and Stability

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“…Polymer-metal structures are of great importance in thermal management of microsystems [11]. The biopolymer poly( l -lactic acid) (PLLA) in combination with various types of treatment procedures, grafting or metal layer deposition, can be applied in the preparation of substrates for tissue engineering [12,13]. Different polymer substrates (e.g.…”

Section: Introductionmentioning

confidence: 99%

A novel method for biopolymer surface nanostructuring by platinum deposition and subsequent thermal annealing

et al. 2012

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A novel procedure for biopolymer surface nanostructuring with defined surface roughness and pattern dimension is presented. The surface properties of sputtered platinum layers on the biocompatible polymer poly(l-lactic acid) (PLLA) are presented. The influence of thermal treatment on surface morphology and electrical resistance and Pt distribution in ca. 100 nm of altered surface is described. The thickness, roughness and morphology of Pt structures were determined by atomic force microscopy. Surface sheet resistance was studied by a two-point technique. It was the sequence of Pt layer sputtering followed by thermal treatment that dramatically changed the structure of the PLLA’s surface. Depending on the Pt thickness, the ripple-like and worm-like patterns appeared on the surface for thinner and thicker Pt layers, respectively. Electrokinetic analysis confirmed the Pt coverage of PLLA and the slightly different behaviour of non-annealed and annealed surfaces. The amount and distribution of platinum on the PLLA is significantly altered by thermal annealing.

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Nanostructuring of polymethylpentene by plasma and heat treatment for improved biocompatibility

Cited by 48 publications

References 27 publications

Surface Modification of Polymer Substrates for Biomedical Applications

Surface Modification of Polymer Substrates for Biomedical Applications

Plasma activated perfluoroethylenepropylene for cytocompatibility enhancement

A novel method for biopolymer surface nanostructuring by platinum deposition and subsequent thermal annealing

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