Nanostructured physical gel of SBS block copolymer and Ag/DT/SBS nanocomposites

Peponi, Laura; Tercjak, Agnieszka; Torre, Luigi; Mondragón, Iñaki; Kenny, J. M.

doi:10.1007/s10853-009-3277-2

Cited by 15 publications

(3 citation statements)

References 33 publications

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“…Several studies pointed out the improvement of bioactivity of scaffolds by nanoparticles owing to the larger surface area [31][32][33][34][35]. Some of them, like iron oxide super-paramagnetic nanoparticles, quantum dots (QDs), or nanodiamonds, are capable for bioimaging [36][37][38][39][40]. Furthermore, carbon-based nanoforms such as carbon nanotubes (CNTs), graphene oxide, etc, and their demonstrated efficiency as fillers or reinforcements, are found to have inherent potential in fabricating scaffolds for tissue engineering applications.…”

Section: Nanotechnology In Tissue Engineeringmentioning

confidence: 99%

“…Furthermore, carbon-based nanoforms such as carbon nanotubes (CNTs), graphene oxide, etc, and their demonstrated efficiency as fillers or reinforcements, are found to have inherent potential in fabricating scaffolds for tissue engineering applications. In addition, polymeric nanocomposites are also coupled with inorganic/organic fillers to improve efficacy [39,40].…”

Section: Nanotechnology In Tissue Engineeringmentioning

confidence: 99%

See 1 more Smart Citation

Recent advancements in polymer matrix nanocomposites for bone tissue engineering applications

Sagadevan

Schirhagl

Rahman

et al. 2023

Journal of Drug Delivery Science and Technology

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Section: Nanotechnology In Tissue Engineeringmentioning

confidence: 99%

Section: Nanotechnology In Tissue Engineeringmentioning

confidence: 99%

Recent advancements in polymer matrix nanocomposites for bone tissue engineering applications

Sagadevan

Schirhagl

Rahman

et al. 2023

Journal of Drug Delivery Science and Technology

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“…Nanotehnologija uključuje materijale koji poseduju makar jednu dimenziju na nanometarskom nivou i pomoću kojih se mogu praviti strukture, uređaji i sistemi novih karakteristika. Uopšteno rečeno polimerni nanokompoziti su rezultat kombinacije polimera i biomaterijala na nanometarskom nivou (85,86). Interakcija između nanostruktura i polimernog matriksa je osnova za poboljšanje mehaničkih i funkcionalnih karakteristika nanokompozita u poređenju sa konvencionalnim mikrokompozitima.…”

Section: Savremeni Koncepti Konstrukcije Skafoldaunclassified

Biological activity of the compound scaffolds based on highly porous hydroxyapatite and their influence on bone tissue engineering

Petrović¹

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Želeo bih da se zahvalim:Svom mentoru Prof. dr Miroslavu Vukadinoviću, na podršci koju mi pruža od mog prvog dana susreta sa maksilofacijalnom hirurgijom, na prijateljskim, stručnim i ljudskim savetima i na pomoći koju mi je pružio u mom usavršavanju i napredovanju u hirurgiji. Velika mi je čast i privilegija što sam svoje prve ozbiljne samostalne hirurške intervencije uradio pod njegovim budnim nadzorom.Ko-mentoru Prof. dr Dejanu Markoviću, jer me je uveo u svet nauke o inženjerstvu tkiva i svojim znanjem, iskustvom i prijateljskim savetima inspirisao u izradi ove disertacije.Dr Vukomanu Jokanoviću, na bezuslovnoj pomoći, entuzijazmu i optimizmu koji je preneo i na mene tokom ove studije. Doc. dr Jeleni Sopti, na dragocenim idejama i pomoći u obradi histoloških preparata.Dr Aleksandri Konić, na trudu i pomoći u izradi laboratorijskog dela doktorata.Prof. dr Petru Milosavljeviću na prijateljskoj pomoći koju mi je pružio na Veterinarskom fakultetu u Beogradu. Prof. dr Zvezdani Kojić, na pomoći u izvođenju doktorata. Dr Ivanu Soldatoviću, na stručnim i prijateljskim savetima i pomoći da se izborim sa statističkim problemima.Dr Nebojši Nikoliću, na drugarskim savetima i na rečima podrške kad mi je bilo najpotrebnije.Jovanu, Branku i Jelisaveti na radosti koju mi donose svaki dan. Jeleni na ljubavi, razumevanju i strpljenju.A najveću zahvalnost dugujem svojim roditeljima, Branku i Dušanki, što su bili to što jesu u mom životu!The results showed that the examined scaffolds were perfectly designed and they had the ideal surface morphology which had an impact on how the hydroxyapatite deposit as well as on the material surface activity necessary for scaffolds. The examined materilas indicated the presence of cytotoxicity in indirect contact with cell culture, but also showed that their surfaces, in direct contact with cell culture, are suitable for cell adhering and their proliferation, and furthermore, they have features which enable the cell growth. The results of the test of local effects on skin in rabbits, showed that none of the examined materilas causes irritation and can be considered as non-irritating, so due to that fact they are suitable for in vivo application. The porouse hydroxyapatite and compound scaffold pHAP with PLGA led to the creation of the new bone together with considerable presence of mineralization in critical sized defects. According to this reasearch, pHAP with PLGA has proved to be equal, and to certain parameters, even better than the applied BioOss R golden standard. pHAP with metformin did not show expected results.The research has shown that, in further experiments, pHAP together with PLGA can be the basis for generating the scaffold in bone tissue engineering and provide settlement of osteoblasts or any of osteoblast precursors, their growth and differentiation.

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Recent Advances in Nanostructured Polymers

Singh

Shagolsem

2022

Materials Horizons: From Nature to Nanomaterials

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Nanostructured physical gel of SBS block copolymer and Ag/DT/SBS nanocomposites

Cited by 15 publications

References 33 publications

Recent advancements in polymer matrix nanocomposites for bone tissue engineering applications

Recent advancements in polymer matrix nanocomposites for bone tissue engineering applications

Biological activity of the compound scaffolds based on highly porous hydroxyapatite and their influence on bone tissue engineering

Recent Advances in Nanostructured Polymers

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