Nanostructured lipid carrier for bioactive rice bran gamma-oryzanol

Villar, Mary Annilyn L.; Vidallon, Mark Louis P.; Rodriguez, Evelyn B.

doi:10.1016/j.fbio.2022.102064

Cited by 7 publications

(2 citation statements)

References 47 publications

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“…Furthermore, this characteristic was preserved by over 90% after 60 days under light and ambient temperature conditions. The obtained results indicate that this material functions as a rapid-triggered release system, as well as a colloidal nanocarrier for prolonged GO release (Villar et al 2022).…”

Section: Bioactivesmentioning

confidence: 78%

Rice waste feedstocks: A review of alternatives for their conversion into high-value added products

Sanoja-López,

Loor-Molina,

Luque

2023

BioRes

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The increase in global population, expected daunting energy demands, and scarcity of resources has driven the search for new sustainable sources of materials, energy, and chemicals. In this context, biomass valorization has emerged as a promising technology to obtain high-value products in recent years. This research focuses on the valorization of rice production waste including straw, husk, and bran, due to their abundance, underutilization, and potential in generating a wide range of valuable products such as biofuels and materials. A systematic review was conducted regarding the valorization of rice production waste. The characteristics of biomass obtained from post-harvest rice production were explored, as well as the primary products derived from each of the discussed biomass feedstocks. Furthermore, the economic viability of the obtained products in their respective fields of application was evaluated, providing a solid foundation for future research and industrial applications. Different rice waste materials studied hold significant potential to obtain high‑value products including silica, adsorbent materials, biofuels, and various bioactive compounds.

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Section: Bioactivesmentioning

confidence: 78%

Rice waste feedstocks: A review of alternatives for their conversion into high-value added products

Sanoja-López,

Loor-Molina,

Luque

2023

BioRes

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“…Drugs that are both lipophilic and hydrophilic can be transported simultaneously using NLC. 20,21 6. Good physical and chemical stability as well as high encapsulation efficiency.…”

Section: Advantages Of Nlcmentioning

confidence: 99%

Nanostructured Lipid Carriers: A Potential Era of Drug Delivery Systems

Chinthaginjala,

Bogavalli,

Hindustan

et al. 2023

Ind. J. Pharm. Edu. Res

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Nanotechnology is rapidly evolving in the development of new drug delivery systems. Nanostructured lipid carriers are the second era of Solid Lipid Nanoparticles (SLN). These are the alternative carrier system over the solid lipid nanoparticles. Nanostructured lipid carriers are composed of a mixture of solid and liquid lipids, resulting in a solely crystallized lipid system with various advantages over solid lipid nanoparticles, such as higher drug entrapment efficiency, drug release modification versatility, and improved stability. Lipid biocompatibility is responsible for their evolution as a viable drug delivery technology. It was observed that it had superior qualities to other lipid compositions. Various drug-distribution technologies have arisen in the last few decades, with the improvement of nanoscale drug-delivery devices being a fascinating component of this. This review explains the nanostructured lipid carriers in terms of structure, fabrication methods, characterization, future developments, wide applications, patents, and benefits over first-generation lipid nanoparticles. The review is primarily concerned with the forthcoming view of nanostructured lipid carriers and their specificity for various physiological affinities. Several polymers have been used in the development of nanoparticles for drug delivery research to maximize medicinal effectiveness while limiting negative effects. Because of their biological non-toxicity, non-immunogenicity, and compatibility, nanostructured lipid carriers will be the most intensively studied lipid nanocarrier systems.

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Zein nanoencapsulation enhances the antifungal activity of thymol for postharvest decay control in bananas

Punelas–Villanueva,

Almeda,

Chua

et al. 2024

emergent mater.

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The current work describes a nanoparticle system-based approach to enhance the antifungal activity of thymol, a ubiquitous natural antifungal phenolic compound, in postharvest control against banana anthracnose. Thymol was encapsulated within the amphiphilic protein zein by high-shear emulsification, yielding highly dispersible thymol-loaded zein nanoparticles with a high encapsulation efficiency (70%). These particles have an average diameter of 300 nm with spherical morphology, smooth interface, and matrix-type internal structure, as supported by comprehensive structural characterization (dynamic light scattering, transmission electron microscopy and atomic force microscopy). Based on a 40-d storage stability test, thymol was effectively retained within the nanoparticles at 4 °C and ambient room temperature (99% and 97% retention, respectively), despite thymol’s instability and volatility. Antifungal activity assessment against Colletotrichum musae, one of the predominant pathogens that cause banana anthracnose, showed a 200- to 300-fold improvement in the in vitro antifungal activity of thymol. Moreover, the application of thymol-loaded zein nanoparticles as a spray component for banana postharvest treatment demonstrated the efficacy of thymol-loaded zein nanoparticles in preventing and delaying the formation of initial symptoms of banana anthracnose. This appears to arise from the thymol-loaded zein nanoparticles depositing as a film on the banana epidermis, as revealed by atomic force microscopy. Overall, this nanoparticle system offers a new avenue for the design of effective antifungal materials with potential applications in combatting postharvest diseases. Graphical abstract

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Nanostructured lipid carrier for bioactive rice bran gamma-oryzanol

Cited by 7 publications

References 47 publications

Rice waste feedstocks: A review of alternatives for their conversion into high-value added products

Rice waste feedstocks: A review of alternatives for their conversion into high-value added products

Nanostructured Lipid Carriers: A Potential Era of Drug Delivery Systems

Zein nanoencapsulation enhances the antifungal activity of thymol for postharvest decay control in bananas

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