Nanosol SERS quantitative analytical method: A review

Li, Dan; Yao, Dongmei; Li, Chongning; Luo, Yanghe; Liang, Aihui; Wen, Guiqing; Jiang, Zhiliang

doi:10.1016/j.trac.2020.115885

Cited by 71 publications

(37 citation statements)

References 144 publications

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“…As an important area of research, there are excellent reviews which give comprehensive accounts of the progress that has been made in the fabrication of particular types of multifunctional SERS substrate. [64][65][66][67] Therefore, this review is not intended to be comprehensive but rather targets to bring together the state-of-the-art research trends in constructing the four main types of multifunctional SERS substrates listed above with the hopes to inspire novel substrate designs which move SERS closer towards real-life practice. More specifically, we discuss research performed within the past five years to highlight the key strategies used for constructing each type of multifunctional SERS substrates, as well as their advantages, effectiveness and practicality.…”

Section: Introductionmentioning

confidence: 99%

Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates

Huang

et al. 2021

J. Mater. Chem. C

105

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Section: Introductionmentioning

confidence: 99%

Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates

Huang

et al. 2021

J. Mater. Chem. C

105

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“…Reproducibility of surface‐enhanced Raman scattering (SERS) techniques was greatly affected by the stability of SERS substrate, [ 4,55 ] and the corrosion resistance performance of GIAAN@PEG under different conditions was therefore studied by UV‐vis spectroscopies. For comparison, citrate‐stabilized Ag NPs (Figures S3D—S3F) with bright yellow were prepared.…”

Section: Resultsmentioning

confidence: 99%

Versatile Graphene‐Isolated AuAg‐Nanocrystal for Multiphase Analysis and Multimodal Cellular Raman Imaging^†

Zhu

Cai

et al. 2021

Chin. J. Chem.

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Surface-enhanced Raman spectroscopy | Graphene-isolated AuAg-nanocrystal | Self-assembly | Multiphase analysis | Multimodal cellular Raman imaging Surface-enhanced Raman spectroscopy (SERS)-based bioanalytical technique involves the interaction of SERS-active substrate with complex environment, which has aroused intensive research interests. Compared to the commonly used Au SERS substrates, Ag nanocrystals have larger optical absorption cross section and acceptable price, but they possess poor oxidation resistance and potential biotoxicity, and the occurrence of unnecessary chemical reactions is inevitable due to the direct contact with probe molecules. Herein, we report a graphene-isolated AuAg nanocrystal (GIAAN) with the SERS-active AuAg core confined in a nanospace of few-layer graphene shell, which possesses unique Raman peaks, high SERS activity, excellent stability, superior fluorescence quenching performance and good biocompatibility. Based on the limited solubility of GIAAN in water and organic solvents, it is able to spontaneously generate interfacial self-assembled GIAAN (ISA-GIAAN) film at immiscible two-phase interfaces without any inducer, and multiphase Raman analysis of both water-and lipid-soluble drug model molecules is further achieved. Moreover, the GIAAN is further non-covalently functionalized with polyoxyethylenestearyl ether (C 18 -PEG) to acquire GIAAN@PEG with good water-solubility for SERS quantitative analysis in homogeneous system and multimodal Raman imaging of MCF-7 cells. We expect the versatile GIAAN holds great potential to monitor drug metabolism and guide intended drug delivery in clinic trials.

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“…2 B presents the typical procedure of SERS metabolite detection: firstly, the metabolite samples are collected and added onto the SERS-active nanostructures for molecular adsorption; then, the exposure of samples to laser excitations induces high SERS signal, which can be detected by the Raman spectrometer; finally, the obtained SERS signals are processed and analyzed for quantification. The design of SERS substrates follows the guidelines of generating more plasmonic hotspots [ [85] , [86] , [87] , [88] ]. As shown in Fig.…”

Section: Main Metabolic Molecules Detecting Methodsmentioning

confidence: 99%

Human metabolite detection by surface-enhanced Raman spectroscopy

Liu

2022

Materials Today Bio

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Metabolites are important biomarkers in human body fluids, conveying direct information of cellular activities and physical conditions. Metabolite detection has long been a research hotspot in the field of biology and medicine. Surface-enhanced Raman spectroscopy (SERS), based on the molecular “fingerprint” of Raman spectrum and the enormous signal enhancement (down to a single-molecule level) by plasmonic nanomaterials, has proven to be a novel and powerful tool for metabolite detection. SERS provides favorable properties such as ultra-sensitive, label-free, rapid, specific, and non-destructive detection processes. In this review, we summarized the progress in recent 10 years on SERS-based sensing of endogenous metabolites at the cellular level, in tissues, and in biofluids, as well as drug metabolites in biofluids. We made detailed discussions on the challenges and optimization methods of SERS technique in metabolite detection. The combination of SERS with modern biomedical technology were also anticipated.

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Nanosol SERS quantitative analytical method: A review

Cited by 71 publications

References 144 publications

Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates

Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates

Versatile Graphene‐Isolated AuAg‐Nanocrystal for Multiphase Analysis and Multimodal Cellular Raman Imaging^†

Human metabolite detection by surface-enhanced Raman spectroscopy

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Nanosol SERS quantitative analytical method: A review

Cited by 71 publications

References 144 publications

Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates

Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates

Versatile Graphene‐Isolated AuAg‐Nanocrystal for Multiphase Analysis and Multimodal Cellular Raman Imaging†

Human metabolite detection by surface-enhanced Raman spectroscopy

Contact Info

Product

Resources

About

Versatile Graphene‐Isolated AuAg‐Nanocrystal for Multiphase Analysis and Multimodal Cellular Raman Imaging^†