Nanoscale insight into biochemical changes in cervical cancer cells exposed to adaptogenic drug

Pięta, Ewa

doi:10.1016/j.micron.2023.103462

Cited by 3 publications

(1 citation statement)

References 47 publications

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“…Beyond the studies summarized here, AFM-IR has also been applied to red blood cells (including pathological states) ,− and cancer cells, − as well as on isolated viruses. , …”

Section: Recent Applications To the Life Sciencesmentioning

confidence: 99%

AFM-IR for Nanoscale Chemical Characterization in Life Sciences: Recent Developments and Future Directions

V. D. dos Santos,

Hondl,

Ramos-Garcia

et al. 2023

ACS Meas. Sci. Au

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Despite the ubiquitous absorption of mid-infrared (IR) radiation by virtually all molecules that belong to the major biomolecules groups (proteins, lipids, carbohydrates, nucleic acids), the application of conventional IR microscopy to the life sciences remained somewhat limited, due to the restrictions on spatial resolution imposed by the diffraction limit (in the order of several micrometers). This issue is addressed by AFM-IR, a scanning probe-based technique that allows for chemical analysis at the nanoscale with resolutions down to 10 nm and thus has the potential to contribute to the investigation of nano and microscale biological processes. In this perspective, in addition to a concise description of the working principles and operating modes of AFM-IR, we present and evaluate the latest key applications of AFM-IR to the life sciences, summarizing what the technique has to offer to this field. Furthermore, we discuss the most relevant current limitations and point out potential future developments and areas for further application for fruitful interdisciplinary collaboration.

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“…Beyond the studies summarized here, AFM-IR has also been applied to red blood cells (including pathological states) ,− and cancer cells, − as well as on isolated viruses. , …”

Section: Recent Applications To the Life Sciencesmentioning

confidence: 99%