Nanoscale bioconjugates: A review of the structural attributes of drug-loaded nanocarrier conjugates for selective cancer therapy

Effects of morphology and size of nanoscale drug carriers on cellular uptake and internalization process: a review

“…[46][47][48][49] This advantage also enhances smart and targeted drug delivery. 50 Nanoscaled small particles can improve drug concentration inside a tumor with privileged aggregation based on the large pore size and awed lymphatic system of the neovasculature, described as upgraded permeation and retention efficiency. 51 Additionally, nanotechnologybased drug delivery is a novel way to overcome the therapy bottleneck for cardiovascular disease due to the fast growth of nanoscience and the exceptional performance of nanomaterials.…”

Synergies in antimicrobial treatment by a levofloxacin-loaded halloysite and gold nanoparticles with a conjugation to a cell-penetrating peptide

“…In the field of advanced drug delivery, utilization of the natural-based micro and nanomaterials for encapsulation of the target drug has prospered due to the brilliant excellences, as follows; showing more structural stability than the artificial species like metal-organic frameworks, [1][2][3] having high levels of biodegradability and compatibility, 4,5 capability to combine with the organic and inorganic materials, 6,7 sensitivity to the external stimuli such as heat and pH. 8,9 Moreover, the surface of this type of materials can be chemically modified and functionalized for further conjugations.…”

A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells

“…Recently, we have studied the synergistic therapeutic effects of applying magnetic direction of the cargos to the targeted tissue and controlled release of Taxotere (TXT) by plasmonic photothermal stimulation of the AuNPs 30 . The AuNPs play a dual-edged role in the cancer therapy: (1) tumor metastasis inhibition that is considered as a biological function 31 , and (2) plasmonic photothermal therapy (PPTT) that is implemented through an exclusive capability of the AuNPs calling LSPR effect (LSPR stands for localized surface plasmonic resonance), and is considered as a physicochemical property of the AuNPs 32 , 33 . PPTT provides a fantastic opportunity to efficiently penetrate the adipose tissue of the cancerous masses by heating the AuNPs under irradiation of a specific wavelength 34 .…”