Nanorobotics in Drug Delivery Systems for Treatment of Cancer: A Review

Luz, Glécia Virgolino da Silva; Barros, Kleber Vânio Gomes; Araújo, Fábio Vladimir Calixto de; Silva, Gabriela Barbosa da; Silva, Pedro Augusto Ferreira da; Condori, Roxana Claudia Iquize; Brasil, L. M.

doi:10.17265/2161-6213/2016.5-6.005

Cited by 19 publications

(10 citation statements)

References 52 publications

(58 reference statements)

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“…Chromallocyte: The Chromallocyte would replace entire chromosomes in individual cells thus reversing the effects of genetic disease and other accumulated damage to our genes, preventing aging. Inside a cell, repair machine will first size up the situation by examining the cell's contents and activity, and then take action by working along molecule-by-molecule and structure-by structure; repair machines will be able to repair the whole cell [3]. The major requirement for the nanorobot is, of course, power.…”

Section: Types Of Nanorobotsmentioning

confidence: 99%

“…Most of the anti-cancer drugs like Doxorubicin are used in several types of cancer, such as HD (Hodgkin's disease), in which treatment is administered in combination with other antineoplastic agents in order to reduce their toxicity. Considering the properties of nanorobots to navigate as blood borne devices, they can help on such extremely important aspects of cancer therapy [8]. Nanorobots with embedded chemical biosensors can be used to perform detection of tumour cells in early stages of development inside the patient's body.…”

Section: Application Of Nano Robots In Cancer Treatmentmentioning

confidence: 99%

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A Research on Future Scenario in the Field Of Role of Nanorobotics a Device for Diagnosis and Treatment

Chouhan¹

2023

Glob Acad J Med Sci

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Nanorobots are the nano devices that are used for protecting or treatment against pathogens in humans. The use of nanorobots technology has become familiar and increasingly common, especially with pharmaceutical technology. We conducted this research paper by observing the different types of reviews, as well as conducting and evaluating literature review papers. This research is provided detailed overview of the types, properties and application of nanorobot in the diagnosis, prevention and treatment of various diseases. Nanorobots technology is rapidly emerging in the medical field, and this subfield has been termed nanomedicine. Nanorobotics are developing wide potential applications across all fields of medicine, and expanding the number of therapeutic options available, while also improving the efficacy of existing treatments. The most recent applications of these devices include targeted drug delivery to the brain, glucose monitoring in patients with diabetes, bone reconstruction, cancer treatment, blood clot removal, nerve regeneration and protein peptide based drug delivery systems.

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Section: Types Of Nanorobotsmentioning

confidence: 99%

Section: Application Of Nano Robots In Cancer Treatmentmentioning

confidence: 99%

A Research on Future Scenario in the Field Of Role of Nanorobotics a Device for Diagnosis and Treatment

Chouhan¹

2023

Glob Acad J Med Sci

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“…It is made out of a tank with a shutter covering it, from which dye molecules can escape when the lid is evenly opened. This device, which is natural and made of beta-cyclodextrins, organometallic compounds, and silica (SiO2), will be employed for therapeutic applications [16].…”

Section: Nanorobots and Their Typesmentioning

confidence: 99%

Disease Fighting Machines Inside the Body: A Review

Belachew

2023

BJSTR

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Background: Nanotechnology will bring about a revolution in the globe. The National Nanotechnology Initiative (NNI) defines nanotechnology as the study of all particles with a dimension of 100 nanometers or less. One of the main advantages of smaller particles is the rise in the ratio of surface atoms or molecules to total number. Due to their large surface area, which enhances surface activity and alters their biological and physical features, they have many surfaces. Drugs having nanoscalesized active ingredients are referred to as nanotechnology applications in the pharmaceutical sector. They can repair damaged tissue at the cellular level, are helpful in detecting, diagnosing, and treating illness, and are beneficial in treating severe diseases like HIV, cancer, and others. Drugs can now be injected into previously inaccessible areas of the body thanks to smaller drug delivery systems, which are also essential for the treatment and early diagnosis of specific diseases like cancer. Target treatment, a recent development in pharmaceutical administration, improves medical equipment and diagnostic techniques.

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“…As drug carriers for prompt dosage regimens, nanorobots enable the maintenance, as required, of chemicals into the bloodstream for a longer period of time. Therefore, they provide the expected pharmacokinetic parameters for anticancer chemotherapy [13,15,85,86]. For molecular detection, diagnosis, and destruction in the initial phases of cancer progress of metastatic or malignant tumor cells, nanorobots often need a biosensing component.…”

Section: Ai-based Nanorobots For Drug Deliverymentioning

confidence: 99%

Enhancing Clinical Translation of Cancer Using Nanoinformatics

Soltani

Kashkooli

Souri

et al. 2021

Cancers

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Application of drugs in high doses has been required due to the limitations of no specificity, short circulation half-lives, as well as low bioavailability and solubility. Higher toxicity is the result of high dosage administration of drug molecules that increase the side effects of the drugs. Recently, nanomedicine, that is the utilization of nanotechnology in healthcare with clinical applications, has made many advancements in the areas of cancer diagnosis and therapy. To overcome the challenge of patient-specificity as well as time- and dose-dependency of drug administration, artificial intelligence (AI) can be significantly beneficial for optimization of nanomedicine and combinatorial nanotherapy. AI has become a tool for researchers to manage complicated and big data, ranging from achieving complementary results to routine statistical analyses. AI enhances the prediction precision of treatment impact in cancer patients and specify estimation outcomes. Application of AI in nanotechnology leads to a new field of study, i.e., nanoinformatics. Besides, AI can be coupled with nanorobots, as an emerging technology, to develop targeted drug delivery systems. Furthermore, by the advancements in the nanomedicine field, AI-based combination therapy can facilitate the understanding of diagnosis and therapy of the cancer patients. The main objectives of this review are to discuss the current developments, possibilities, and future visions in naoinformatics, for providing more effective treatment for cancer patients.

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Nanorobotics in Drug Delivery Systems for Treatment of Cancer: A Review

Cited by 19 publications

References 52 publications

A Research on Future Scenario in the Field Of Role of Nanorobotics a Device for Diagnosis and Treatment

A Research on Future Scenario in the Field Of Role of Nanorobotics a Device for Diagnosis and Treatment

Disease Fighting Machines Inside the Body: A Review

Enhancing Clinical Translation of Cancer Using Nanoinformatics

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